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Background: Higher social support protects people from developing mental disorders. Limited evidence is available on the mechanism through which social support plays this protective role.
Objective: To investigate the stress-buffering process of social support on depressive symptoms using a novel longitudinal dynamic symptom network approach.
Methods: A total of 4242 adult participants who completed the first two waves (from May to October 2020) of the International Covid Mental Health Survey were included in the study. Cross-lagged panel network modelling was used to estimate a longitudinal network of self-reported social support, loneliness and depressive symptoms. Standardised regression coefficients from regularised cross-lagged regressions were estimated as edge weights of the network.
Findings: The results support a unidirectional protective effect of social support on key depressive symptoms, partly mediated through loneliness: A higher and was associated with decreased (weight=-0.033) and symptoms (weight=-0.038). Support from others was also negatively associated with loneliness, which in turn associated with decreased (weight=0.086) and (weight=0.077). We identified a greater number of direct relationships from social support to depressive symptoms among men compared with women. Also, the edge weights from social support to depression were generally stronger in the men's network.
Conclusions: Reductions in negative self-appraisal might function as a bridge between social support and other depressive symptoms, and, thus, it may have amplified the protective effect of social support. Men appear to benefit more from social support than women.
Clinical Implications: Building community-based support networks to deliver practical support, and loneliness reduction components are critical for depression prevention interventions after stressful experiences.
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http://dx.doi.org/10.1136/bmjment-2023-300802 | DOI Listing |
Turk J Pediatr
September 2025
Division of Pediatric Infectious Diseases, Faculty of Medicine, İstanbul University, İstanbul, Türkiye.
Aim: This study aimed to describe barriers and facilitators of the adherence of children with human immunodeficiency virus (HIV) to antiretroviral therapy (ART) from the perspectives of their caregivers.
Methods: In-depth interviews were held with the caregivers of 15 children. The collected data were analyzed using thematic analysis procedures.
J Med Internet Res
September 2025
Department of Community Medicine, Faculty of Health, UiT The Arctic University of Norway, Tromsø, Norway.
Background: The ability to access and evaluate online health information is essential for young adults to manage their physical and mental well-being. With the growing integration of the internet, mobile technology, and social media, young adults (aged 18-30 years) are increasingly turning to digital platforms for health-related content. Despite this trend, there remains a lack of systematic insights into their specific behaviors, preferences, and needs when seeking health information online.
View Article and Find Full Text PDFBackground: The study aimed to adapt a stress and well-being intervention delivered via a mobile health (mHealth) app for Latinx Millennial caregivers. This demographic, born between 1981 and 1996, represents a significant portion of caregivers in the United States, with unique challenges due to higher mental distress and poorer physical health compared to non-caregivers. Latinx Millennial caregivers face additional barriers, including higher uninsured rates and increased caregiving burdens.
View Article and Find Full Text PDFPLoS One
September 2025
Centre for Experimental Pathogen Host Research, School of Medicine, University College Dublin, Dublin, Ireland.
Background: Acute viral respiratory infections (AVRIs) rank among the most common causes of hospitalisation worldwide, imposing significant healthcare burdens and driving the development of pharmacological treatments. However, inconsistent outcome reporting across clinical trials limits evidence synthesis and its translation into clinical practice. A core outcome set (COS) for pharmacological treatments in hospitalised adults with AVRIs is essential to standardise trial outcomes and improve research comparability.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Evolution, Ecology, and Organismal Biology, University of California, Riverside, California, United States of America.
There are many benefits for students who participate in undergraduate research experiences, including increased retention and persistence in science, technology, engineering, and mathematics (STEM). By doing research, minoritized students increase their likelihood of pursuing graduate school and STEM careers. The benefits of research experiences are partially mediated by students' interactions with their faculty research mentor.
View Article and Find Full Text PDF