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http://dx.doi.org/10.1007/s00249-023-01690-9 | DOI Listing |
Curr Alzheimer Res
September 2025
Department of Neurology, the Wuxi No. 2 People's Hospital, Jiangnan University Medical Center, Wuxi, Jiangsu Province, China.
Introduction: The complement receptor 1 (CR1) gene is identified as the one closely associated with Alzheimer's disease (AD). However, there has been no exploration of the imaging alterations associated with the CR1 gene in AD patients of the Han population. The purpose of this study is to investigate the association between the rs6656401 mutation and neuroimaging variations in Han AD patients.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Topic: The aim of this systematic review and meta-analysis is to evaluate best-corrected visual acuity (VA) outcomes following transscleral cyclophotocoagulation (TSCPC) in patients with refractory glaucoma.
Clinical Relevance: TSCPC is typically reserved for cases of refractory glaucoma, due to apprehension of negative affects on VA. Prior studies have reported the VA outcomes from TSCPC, but no comprehensive review of the literature has yet been conducted.
Am J Ophthalmol
September 2025
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address:
Purpose: To report on the real-world experience of using intravitreal pegcetacoplan for the treatment of geographic atrophy (GA) in age-related macular degeneration (AMD).
Design: Retrospective interventional case series.
Methods: Eyes with symptomatic GA secondary to AMD were treated with 15mg of intravitreal pegcetacoplan and participated in an ongoing prospective swept-source optical coherence tomography angiography (SS-OCTA) imaging study.
Hum Reprod Update
September 2025
Women's Health Research Collaborative, New York, NY, USA.
Background: Reproductive-age women with intrauterine adhesions (IUAs) following uterine surgery may be asymptomatic or may experience light or absent menstruation, infertility, preterm delivery, and/or peripartum hemorrhage. Understanding procedure- and technique-specific risks and the available evidence on the impact of surgical adjuvants is essential to the design of future research.
Objective And Rationale: While many systematic reviews have been published, most deal with singular aspects of the problem.
Public Health Rep
September 2025
Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Objective: Rare diseases collectively affect approximately 30 million people in the United States. Despite advances in genomic medicine, early diagnosis is challenging because of limited awareness of, accessibility to, and disparities in health care resources. We assessed the real-world experiences of patients with rare diseases in Pennsylvania and evaluated the effect of delayed diagnosis on psychosocial and financial burdens.
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