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The spine is one of the most important structures in the human body, serving to support the body, organs, protect nerves, etc. Medical image segmentation for the spine can help doctors in their clinical practice for rapid decision making, surgery planning, skeletal health diagnosis, etc. The current difficulty is mainly the poor segmentation accuracy of skeletal Magnetic Resonance Imaging (MRI) images. To address the problem, we propose a spine MRI image segmentation method, Atrous Spatial Pyramid Pooling (ASPP)-U-shaped network (UNet), which combines an ASPP structure with a U-Net network. This approach improved the network feature extraction by introducing an ASPP structure into the U-Net network down-sampling structure. The medical image segmentation models are trained and tested on publicly available datasets and obtained the Dice coefficient and Mean Intersection over Union coefficients with 0.866 and 0.755, respectively. The experimental results show that ASPP-UNet has higher accuracy for spine MRI image segmentation compared with other mainstream networks.
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http://dx.doi.org/10.3934/mbe.2023713 | DOI Listing |
Mult Scler
September 2025
Neuroimaging Unit, Neuroimmunology Division, Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Neurology, VA Medical Center, TN Valley Healthcare System, Nashville, TN, USA.
Background: There is limited knowledge on the post-glymphatic structures such as the parasagittal dural (PSD) space and the arachnoid granulations (AGs) in multiple sclerosis (MS).
Objectives: To evaluate differences in volume and macromolecular content of PSD and AG between people with newly diagnosed MS (pwMS), clinically isolated syndrome (pwCIS), or radiologically isolated syndrome (pwRIS) and healthy controls (HCs) and their associations with clinical and radiological disease measures.
Methods: A total of 69 pwMS, pwCIS, pwRIS, and HCs underwent a 3.
Adv Radiat Oncol
October 2025
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Radiation Oncology and Radiotherapy, Augustenburger Platz 1, 13353 Berlin, Germany.
Purpose: To evaluate the impact of an optimized online adaptive radiation therapy workflow on physician involvement.
Methods And Materials: Data from a prospective phase 2 trial involving 34 prostate cancer patients treated with cone beam computed tomography (CBCT)-based online adaptive radiation therapy (62 Gy in 20 fractions) were analyzed. Manual interventions were required for 2 steps in the workflow: radiation therapy technologist review and adjustment of automatically segmented organs, guiding target segmentation, so-called "influencer," while physicians reviewed and refined the targets.
Front Endocrinol (Lausanne)
September 2025
Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Objectives: To evaluate whether q-Dixon sequence-based fat fraction (FF) values of the lumbar spine can predict osteoporotic vertebral compression fracture (OVCF) risk in older adult(s) osteoporosis patients.
Materials & Methods: Thirty OVCF patients and 15 osteoporosis patients were enrolled. Areas of interest (ROIs) were manually drawn using the post-processing workstation, and FF values of the patient's L1-L4 vertebrae (except the fractured vertebrae) were measured.
Front Vet Sci
August 2025
Pathobiology and Population Science, Royal Veterinary College, Hatfield, United Kingdom.
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma (NHL) in humans, accounting for about 30-40% of NHL cases worldwide. Canine diffuse large B-cell lymphoma (cDLBCL) is the most common lymphoma subtype in dogs and demonstrates an aggressive biologic behaviour. For tissue biopsies, current confirmatory diagnostic approaches for enlarged lymph nodes rely on expert histopathological assessment, which is time-consuming and requires specialist expertise.
View Article and Find Full Text PDFIndian J Nucl Med
August 2025
Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.
Metastatic renal osteosarcoma is a rare entity. We report a case of a 52-year-old male postright nephrectomy status presented to us with metastatic renal osteosarcoma. 18-fluorine- fluorodeoxyglucose (F-FDG) avid lesions were seen in the right renal bed with extension to adjacent hepatic parenchyma.
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