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Article Abstract
We developed a promising mRNA vaccine against severe fever with thrombocytopenia syndrome (SFTS), an infectious disease caused by the SFTS virus that is primarily transmitted through tick bites. Administration of lipid nanoparticle-encapsulated mRNA-Gn successfully induced neutralizing antibodies and T-cell responses in mice. The vaccinated mice were protected against a lethal SFTS virus challenge, suggesting that this mRNA vaccine may be an effective and successful SFTS vaccine candidate.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10618158 | PMC |
| http://dx.doi.org/10.1038/s41541-023-00771-2 | DOI Listing |
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