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Porcine respiratory disease complex is an economically important disease in the swine industry. Early detection of the disease is crucial for immediate response to the disease at the farm level to prevent and minimize the potential damage that it may cause. In this paper, recent studies on the application of artificial intelligence (AI) in the early detection and monitoring of respiratory disease in swine have been reviewed. Most of the studies used coughing sounds as a feature of respiratory disease. The performance of different models and the methodologies used for cough recognition using AI were reviewed and compared. An AI technology available in the market was also reviewed. The device uses audio technology that can monitor and evaluate the herd's respiratory health status through cough-sound recognition and quantification. The device also has temperature and humidity sensors to monitor environmental conditions. It has an alarm system based on variations in coughing patterns and abrupt temperature changes. However, some limitations of the existing technology were identified. Substantial effort must be exerted to surmount the limitations to have a smarter AI technology for monitoring respiratory health status in swine.
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http://dx.doi.org/10.3390/ani13111860 | DOI Listing |
J Thorac Oncol
July 2025
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Introduction: TNM staging systems create prognostic categories by anatomic extent of disease. Whether therapeutically important molecular alterations in NSCLC augment the prognostic information of TNM staging is unclear. To study this, we analyzed molecular data from the ninth edition of the lung cancer staging system.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
Laboratoy of Virology, Microbiology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
Millions of reverse transcription-polymerase chain reaction (RT-PCR) tests have been performed worldwide during the SARS-CoV-2 pandemic, using various protocols. This study evaluates the duration of SARS-CoV-2 RNA detectability by RT-PCR at body temperature and analyzes changes in cycle threshold (Ct) values over time. Positive nasopharyngeal swabs for SARS-CoV-2 RT-PCR ( = 120) with different Ct values were collected from Hospital Universitario 12 de Octubre (Madrid, Spain, 2020).
View Article and Find Full Text PDFJ Eval Clin Pract
September 2025
Department of Clinical Pharmacy, Institute of Pharmacy, Medical Faculty, Leipzig University, Leipzig, Germany.
Rationale: Outcome studies have shown the benefits of inhalation consultations. Therefore, the service of inhalation consultations from pharmacists has been implemented in guidelines. Recently, this service became reimbursable for German community pharmacies.
View Article and Find Full Text PDFCureus
August 2025
Respiratory Medicine, Birmingham Heartlands Hospital (Part of University Hospitals Birmingham NHS Trust), Birmingham, GBR.
We report the management of a 64-year-old male with newly diagnosed bulbar-onset myasthenia gravis (MG) who was hospitalized with acute neuromuscular respiratory insufficiency. This case highlights the challenges in monitoring respiratory function in MG patients, especially in the presence of bulbar and nuchal weakness, and emphasizes the potential utility of single breath-hold time (SBHT) over forced vital capacity (FVC) as a reliable bedside monitoring tool. Despite initial stabilization with intravenous immunoglobulin (IVIG), the patient deteriorated, requiring escalation to the intensive care unit (ICU), and the clinical worsening corresponded with the SBHT rather than with FVC.
View Article and Find Full Text PDFFront Pharmacol
August 2025
Department of Pharmacy, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Dipeptidyl peptidase 1 (DPP1) inhibitors constitute a major advance in respiratory disease therapeutics. Through selective blockade of neutrophil serine protease (NSP) activation, these agents establish novel treatment paradigms for inflammatory respiratory conditions characterized by neutrophil-driven pathology. This comprehensive review examines the development status, clinical efficacy, and safety profile of DPP1 inhibitors in neutrophil-driven diseases, particularly non-cystic fibrosis bronchiectasis (NCFBE) and chronic obstructive pulmonary disease (COPD).
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