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Article Abstract
The correlation between body fat parameters and arterial stiffness is still under debate. This study aimed to examine the associations of body mass index (BMI) and waist circumference (WC) with estimated pulse wave velocity (ePWV). We utilized data from 14,228 subjects (mean age 53.4 ± 16.8 years; 56.9% were female) from the Korean National Health and Nutrition Examination Survey. The ePWV was calculated using a formula based on age and blood pressure. Simple linear correlation analyses revealed significant associations between both BMI and ePWV ( = 0.098; < 0.001) and WC and ePWV ( = 0.291; < 0.001), with a stronger correlation observed between WC and ePWV. Multiple linear regression analysis demonstrated that WC remained significantly associated with ePWV after adjusting for potential confounders ( = 0.020; = 0.001). However, a statistically significant association was not found between BMI and ePWV ( = 0.011; = 0.076). Multiple binary logistic regression analysis further indicated that both higher BMI and WC were independently associated with higher ePWV, but the association was more pronounced between WC and ePWV than between BMI and ePWV. These findings underscore a stronger correlation between visceral obesity (as indicated by WC) and arterial stiffness (as indicated by ePWV) compared to overall obesity (as indicated by BMI). This highlights the potential significance of abdominal obesity in assessing cardiovascular risk.
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| http://dx.doi.org/10.3390/metabo13101082 | DOI Listing |
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Article Synopsis
- The weight-adjusted-waist index (WWI) is a new obesity measurement that may be more effective than body mass index (BMI) for assessing body composition in hypertensive adults.
- A study with 9,753 hypertensive participants found a significant nonlinear relationship between WWI and arterial stiffness, indicating that WWI levels below 10.23 correlated with lower stiffness while levels above indicated higher stiffness.
- Maintaining an optimal WWI range may lower arterial stiffness and cardiovascular risk in hypertensive individuals, but further research is needed to confirm these findings.