Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft tissue sarcomas, with 50% of cases associated with type 1 neurofibromatosis (NF-1). A 27-year-old male patient was referred to our department with an extended right nasal cavity MPNST. The lesion extended to the skull base, intracranial, parapharyngeal space, and infratemporal fossa. NF-1 was also confirmed by a neurologist. The patient was negative for distant metastases. Due to the tumor's proximity to vital structures, it was decided to treat it with chemotherapy and radiotherapy. Nasal cavity MPNSTs are particularly uncommon, with few reported cases. They should be included in the differential diagnosis of nasal masses or recurrent nosebleeds, particularly in patients with NF-1. Careful follow-up is essential to detect early recurrence, which contributes to a better prognosis.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10575678 | PMC |
| http://dx.doi.org/10.7759/cureus.45175 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Adenoid Cystic Carcinoma Treated With Salvage ZAP-X Radiosurgery in Elderly Patients: A Report on a Case Series.
Cureus
August 2025
Department of Oncology, University of Warmia and Mazury in Olsztyn, Olsztyn, POL.
Management of recurrent adenoid cystic carcinoma (ACC) in elderly patients remains challenging due to comorbidities, functional impairments, and anatomically complex tumor locations that complicate surgical access and increase operative risk. The ZAP-X Gyroscopic Radiosurgery System (ZAP Surgical Systems, Inc., San Carlos, CA, USA) offers a highly precise, non-invasive treatment modality, potentially suitable for salvage therapy in previously irradiated fields and in medically inoperable patients.
View Article and Find Full Text PDFMacrophage Migratory Inhibitory Factor May Contribute to the Production of Nitric Oxide in Obstructive Sleep Apnea.
J Sleep Res
September 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Kansai Medical University, Hirakata, Japan.
In obstructive sleep apnea (OSA), repeated airway obstruction alters mucosal inflammation, which increases exhaled nitric oxide (NO) production in the nasal cavity. However, the underlying mechanism remains unclear. Accordingly, we aimed to examine the mechanism underlying NO production in patients with OSA.
View Article and Find Full Text PDFMicrobiota-mediated metabolic alterations reveal bidirectional regulation of the gut-nose axis in mice with allergic rhinitis.
J Microbiol Immunol Infect
September 2025
Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, 238 Jie-Fang Road, Wuhan, Hubei, 430060, PR China; Department of Otolaryngology-Head and Neck Surgery, Central Laboratory, Renmin Hospital of Wuhan University, 238 Jie-Fang Road, Wuhan, Hubei, 430060, PR China.
Background: Microbes and their metabolites are implicated in respiratory diseases, including allergic rhinitis (AR); however, the interaction between the gut and respiratory tract and the role of microbes remains unclear. We investigated the gut and nasal microbiota variations between AR and control mice and their role in the bidirectional regulation of the gut-nasal axis.
Methods: We validated the OVA-induced establishment of an AR mouse model based on nasal symptoms and histopathology.
Volumetric Assessment of Inferior Turbinate and Nasal Floor Morphology in Skeletal Malocclusions: A Cone-Beam Computed Tomography-Based Anatomical Study.
J Stomatol Oral Maxillofac Surg
September 2025
Service de chirurgie maxillo-faciale et plastique, Hôpital de la Croix Rousse - Hopital Femme Mère enfant HCL, Lyon; Service de chirurgie maxillo-faciale et plastique, CHU Nord Saint Etienne.
Background: Alterations in the anatomy of the inferior turbinate and nasal floor have been linked to airway resistance and dento-skeletal malocclusions. Few studies have quantified these relationships using cone-beam computed tomography (CBCT). This study aimed to determine whether the morphology and volume of the inferior nasal turbinate and adjacent structures differ among sagittal dento-skeletal patterns.
View Article and Find Full Text PDFTreatment outcomes in patients with advanced mucosal melanoma in Spain: results from the real-world GEM1801 study.
Melanoma Res
September 2025
Medical Oncology Department, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, Spain.
Patients with mucosal melanoma have lower survival rates than those with cutaneous melanoma. Recent studies have reported lower mucosal melanoma survival rates with the use of immune checkpoint inhibitors (ICIs). This study analyzed ICI treatment outcomes in patients with mucosal melanoma in a real-world context.
View Article and Find Full Text PDF