Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Due to potential toxicity, non-biodegradable polymers used in 3D (3-dimensional) printing of drugs could be dangerous for patient safety and the environment.
Objective: This review aims to investigate the toxicity of non-biodegradable polymers and investigate the use of natural materials as an alternative in 3D printing medicines. The study evaluates the dangers connected to 3D printing.
Methods: A review of the literature on various 3D printing processes, such as inkjet printing, fused filament manufacturing, and extrusion-related 3DP systems, was done for this study. Also, the use of cellulose derivatives and natural materials in 3D printing and their potential as active excipients was proposed.
Results: The review identified potential toxicity risks linked to non-biodegradable polymers used in drug 3D printing. As a potential fix for this issue, the use of natural materials with improved mechanical and thermal properties was explored. The use of cellulose derivatives as an alternative to non-biodegradable polymers in 3D printing pharmaceuticals was also investigated in the study.
Conclusion: This study emphasises the significance of evaluating the risks connected to drug 3D printing and recommends using natural materials as an alternative to non-biodegradable polymers. More study is required to create secure and reliable 3D printing processes for pharmaceuticals.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/0113816128259971230921111755 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of Eco-Friendly Silane-Treated Rice Flour/PBS Biocomposites with ENR-50 as a Compatibilizer: A Study on Phase Morphology, Properties and Biodegradation.
Polymers (Basel)
August 2025
Division of Polymer Engineering and Rubber Industrial Technology, Department of Mechanical Engineering Technology, College of Industrial Technology, King Mongkut's University of Technology North Bangkok, Bangkok 10800, Thailand.
This study investigated the development of biocomposites for use as packaging and film in everyday applications. The utilization of rice flour (RF) as a cheap natural filler in the production of polybutylene succinate (PBS) biocomposites has been shown to reduce environmental issues caused by non-biodegradable plastic waste. The effect of rice flour content on the morphology and properties of PBS and RF biocomposites was comprehensively evaluated.
View Article and Find Full Text PDFAnalysis and optimization of polyhydroxyalkanoates production by environmental bacterial isolates from Nepal.
BMC Microbiol
August 2025
Department of Microbiology, St. Xavier's College, Maitighar, Kathmandu, 44600, Nepal.
The versatile non-biodegradable material plastic has significantly enhanced innovation, but its production heavily relies on fossil fuels and non-renewable resources, which causes severe pollution and ecosystem disruption, highlighting the urgent need for eco-friendly alternatives. Polyhydroxyalkanoates (PHA) are a class of bioplastics that offer a promising solution as biodegradable, environmentally compatible, and versatile biopolymer synthesized by microorganisms using various substrates, aiding in organic waste management. This study was aimed to isolate and profile PHA producing bacteria from diverse sources such as soil, compost, landfill site, and sewage in Nepal.
View Article and Find Full Text PDFUse of hydrophilic pharmaceutical excipients to modulate release of metal ions from silicone elastomers.
Drug Deliv
December 2025
School of Pharmacy, Queen's University Belfast, Belfast, UK.
Silicone elastomers based on polydimethylsiloxane are biocompatible and non-biodegradable thermosetting polymers used in various drug delivery applications, including subdermal implants, vaginal rings, and intrauterine devices. Without exception, all marketed silicone elastomer drug delivery products provide sustained or controlled release of highly hydrophobic small drug molecules, since drug solubility in the silicone matrix is a prerequisite for molecular diffusion and release. We are interested in developing multipurpose silicone elastomer vaginal rings for local administration of metal ions-such as copper and zinc-for non-hormonal contraception and antimicrobial therapy.
View Article and Find Full Text PDFControlled co-delivery of anti-inflammatory drugs from bilayer polymer films coating a meniscus implant.
Drug Deliv Transl Res
August 2025
Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Knee osteoarthritis (OA), a degenerative joint disease, is increasingly prevalent worldwide and often results from a meniscal deterioration that leads to meniscus removal. Replacing the damaged meniscus with a non-biodegradable prosthesis offers an innovative solution to prevent OA progression, particularly in older patients. However, the long-term use of anti-inflammatory drugs for pain relief and prosthesis integration can cause severe off-target side effects.
View Article and Find Full Text PDFA Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics.
Adv Sci (Weinh)
August 2025
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic Engineering Shenzhen University, Shenzhen, 518060, P. R. China.
With the increasing concerns over environmental pollution and healthcare demands, biodegradable materials are showing promising applications in the field of soft robotics. As two fundamental components of soft robots, actuators and soft sensors predominantly rely on non-biodegradable materials for fabrication, which raises significant environmental concerns. This review provides a comprehensive summary of current advancements in the utilization of biodegradable materials for soft robotics sensors.
View Article and Find Full Text PDF