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http://dx.doi.org/10.21037/cco-23-52 | DOI Listing |
Int J Colorectal Dis
August 2025
Department of Colorectal Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, People's Republic of China.
Purpose: This post-hoc analysis of the LASRE trial aims to evaluate the impact of body mass index (BMI) on surgical difficulty and oncological outcomes in patients undergoing laparoscopic or open resection for low rectal cancer.
Methods: The LASRE trial was a multicenter, randomized controlled trial comparing laparoscopic and open surgery for low rectal cancer. Patients aged 18-75 years with rectal adenocarcinoma located within 5 cm of the dentate line were enrolled and stratified into four BMI groups: underweight (BMI < 18.
Int J Colorectal Dis
August 2025
Department of Colorectal Surgery, Fujian Medical University, Union Hospital, 29 Xinquan Road, 350001, Fuzhou, Fujian, People's Republic of China.
Purpose: The textbook outcome has emerged as a valuable metric for quality assessment in oncological surgery. However, its application and impact within randomized controlled trials involving patients with low rectal cancer remain underexplored. This study aimed to investigate the incidence and predictors of textbook outcome in patients with low rectal cancer undergoing laparoscopic or open resection.
View Article and Find Full Text PDFLancet Gastroenterol Hepatol
April 2025
Department of Colorectal Surgery, Fujian Medical University Union Hospital, Fuzhou, China. Electronic address:
Lancet Gastroenterol Hepatol
April 2025
Department for General and Colorectal Surgery, Medical University Lodz, Lodz, Poland.
Lancet Gastroenterol Hepatol
January 2025
Department of Colorectal Surgery, Fujian Medical University Union Hospital, Fuzhou, China. Electronic address:
Background: Laparoscopic surgery is increasingly used for rectal cancer, but the long-term oncological outcomes for low rectal cancer have not been fully established. We aimed to evaluate the 3-year survival outcomes of laparoscopic surgery versus open surgery in the treatment of low rectal cancer.
Methods: This multicentre, randomised, controlled, non-inferiority trial was conducted at 22 tertiary hospitals in China.