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Efficacy, safety, and legal considerations of do-it-yourself artificial pancreas systems: a position statement from italian diabetes societies.
Acta Diabetol
August 2025
Division of Pediatrics, Pediatric Diabetes, Endocrinology and Nutrition, Azienda Socio Sanitaria Territoriale (ASST) Cremona, Largo Priori 1, 26100, Cremona, Italy.
Do-It-Yourself Artificial Pancreas Systems (DIY-APS)-which combine commercially available devices with open-source software-are increasingly used for the management of type 1 diabetes, despite a lack of formal regulatory approval in many jurisdictions, including in Italy. This position statement, endorsed by Italian diabetes societies (Associazione Medici Diabetologici, Societa Italiana di Diabetologia, and Società Italiana di Endocrinologia e Diabetologia Pediatrica) and "Diabete Italia", the national patient association, addresses the efficacy, safety, and legal implications of DIY-APS in Italy. Real-world evidence and clinical trials demonstrate that DIY-APS improves glycemic control and quality of life and reduce fear of hypoglycemia in users.
View Article and Find Full Text PDFA Do-it-yourself System for Scheduled Feeding of Laboratory Rodents in Their Home Cage.
J Vis Exp
June 2025
Department of Biology, University of Massachusetts; Institute of Applied Life Sciences, University of Massachusetts;
Intermittent fasting and research surrounding the influence of timed caloric restriction on body weight regulation and aging outcomes are trending, both in society and in the laboratory. To study time-restricted feeding and/or caloric restriction in the laboratory, allotted quantities of food are dispersed at scheduled time intervals. Current technology for scheduled feeding of rodents involves either specialized cages with gated food entry ports, time-locked digital hoppers, or manual food delivery.
View Article and Find Full Text PDF"I spend more time on the ecosystem than on the disease": caring for the communicative loop with everyday ADM technology through maintenance and modification work.
AI Soc
November 2024
Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014 Copenhagen K, Denmark.
Automated decision-making (ADM) systems can be worn in and on the body for various purposes, such as for tracking and managing chronic conditions. One case in point is do-it-yourself open-source artificial pancreas systems, through which users engage in what is referred to as "looping"; combining continuous glucose monitors and insulin pumps placed on the body with digital communication technologies to develop an ADM system for personal diabetes management. The idea behind these personalized systems is to delegate decision-making regarding insulin to an algorithm that can make autonomous decisions.
View Article and Find Full Text PDFThe Future of Diabetes Care: Exploring the Potential of Bioartificial Pancreas and Do-It-Yourself Artificial Pancreas System Innovations.
Pathobiology
June 2025
Membrane-Protein Interaction Lab, Department of Genetic Engineering, SRM Institute of Science and Technology, Kattankulathur, India.
Background: Type 1 diabetes mellitus (T1D) is an autoimmune disease marked by the destruction of pancreatic β cells, necessitating lifelong management. Current therapies, such as insulin injections and pancreas transplants, are effective but impose significant burdens, driving the need for innovative solutions. Among these, the bioartificial pancreas (BAP) stands out as a promising approach.
View Article and Find Full Text PDFClosed-loop peristaltic micro-pump for flow-through sample injection in capillary electrophoresis.
Talanta
December 2025
School of Life and Environmental Sciences, Guangxi Key Laboratory of Automatic Detecting Technology and Instruments, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, China. Electronic address:
Capillary electrophoresis (CE) is increasingly used in distributed field environmental monitoring, teaching, and citizen science. Consequently, the development of low-cost CE instruments using inexpensive components and do-it-yourself approaches has gained significant attention. Peristaltic micro-pumps (PMPs), with dimensions as small as 15 × 17 × 34 mm, offer advantages such as low cost, compact size, and energy efficiency, making them highly suitable for miniaturized CE instruments with automated flow-through injection.
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