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Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality worldwide, hence significant efforts have been made to establish behavior and risk factors associated with CVD. The American Heart Association proposed a 7-metric tool to promote ideal cardiovascular health (CVH). Recent data demonstrated that a higher number of ideal CVH metrics was associated with a lower risk of CVD, stroke, and mortality. Our study aimed to perform a systematic review and meta-analysis of prospective studies investigating the association of ideal CVH metrics and CVD, stroke, and cardiovascular mortality (CVM) in the general population. Medline and Scopus databases were searched from January 2010 to June 2022 for prospective studies reporting CVH metrics and outcomes on composite-CVD, coronary heart disease, myocardial infarction, stroke, and CVM. Each CVH metrics group was compared to another. Twenty-two studies totaling 3,240,660 adults (57.8% men) were analyzed. The follow-up duration was 12.0 ± 7.2 years. Our analysis confirmed that a higher number of ideal CVH metrics led to lower risk for CVD and CVM (statistically significant for composite-CVD, stroke, and CVM; < 0.05). Conclusion: Even modest improvements in CVH are associated with CV-morbidity and mortality benefits, providing a strong public health message about the importance of a healthier lifestyle.
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http://dx.doi.org/10.3390/jcm12134417 | DOI Listing |
Am J Prev Cardiol
September 2025
Department of Preventive Medicine, NCD Epidemiology Research Center, Shiga University of Medical Science, Otsu, Shiga, Japan.
Background And Aims: The American Heart Association's Life's Essential-8 (LE8) cardiovascular health (CVH) metrics is considered a comprehensive framework for optimal cardiovascular wellbeing. However, its relationship with the progression of subclinical atherosclerosis, like coronary artery calcification (CAC), is not clarified. We investigated the associations of LE8 CVH metrics with the prevalence and progression of CAC in Japanese men.
View Article and Find Full Text PDFJ Am Nutr Assoc
August 2025
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, and Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China.
Objective: The aim of this research was to investigate the effects of cardiovascular health (CVH), genetic predisposition, and their interactions on new-onset type 2 diabetes (T2D) and cardiovascular diseases (CVD) among individuals with prediabetes.
Method: We assessed 26,962 individuals with prediabetes from the UK Biobank. Life's Essential 8 (LE8) was utilized to measure CVH.
Am J Prev Cardiol
September 2025
Division of Cardiovascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Background: The American Heart Association has recently updated its definition of what constitutes cardiovascular health (CVH), known as Life's Essential 8 (LE8). This study evaluated the current status of CVH in US adults using the LE8 score and compared the overall CVH and each CVH metric between the pre-COVID-19 era and the COVID-19 era.
Methods: Participants aged 20 to 79 years without a history of cardiovascular disease in the National Health and Nutrition Examination Survey (NHANES) cycles from 2017 to 2023 were included.
Clin Radiol
July 2025
Department of Clinical Radiology, Morecambe Bay Hospitals Trust, Asthon Road, Lancaster, LA1 4RP, UK.
Complex ventral hernias (CVHs) represent a subset of incisional hernias so large that they can not be reduced by standard operative techniques without an unacceptable risk of recurrence or potentially dangerous complications. They are debilitating to patients, causing pain, sores and immobility and their incidence is increasing worldwide due to rising operation numbers, an ageing population and increased obesity levels. The field of CVH repair has become its own surgical subspeciality, with the development of CVH multidisciplinary team meetings and tertiary hernia repair centres being established across the world.
View Article and Find Full Text PDFInt J Womens Health
August 2025
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.
Objective: This study explores the relationship between Life's Essential 8 (LE8) score and gestational diabetes mellitus (GDM), subsequent diabetes, and mortality, and analyzes the mediating effects of platelet-related indicators and inflammatory markers.
Methods: The study utilized cohort, data from the Nutrition Examination Survey (NHANES), applying logistic regression models and mediation effect analysis to assess the associations between LE8 score and GDM. Potential confounding factors such as age, race, education, PIR, health insurance, and access to healthcare were adjusted to ensure the reliability of the results.