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Obstructive sleep apnea (OSA) is characterized by recurring episodes of pharyngeal collapse, which can partially or completely block airflow during sleep and cause cardiorespiratory and neurological imbalances. Therefore, the purpose of this study was to assess OSA and the relationship between AHI and polysomnographic characteristics in OSA patients. A prospective study was conducted at the Department of Pulmonology and Sleep Medicine for two years. All 216 participants underwent polysomnography, and 175 of them were reported to have OSA (AHI ≥ 5), while 41 of them did not (AHI < 5). ANOVA and Pearson's correlation coefficient test were performed. In terms of the study population's average AHI, Group 1 had 1.69 ± 1.34, mild OSA had 11.79 ± 3.55, moderate OSA had 22.12 ± 4.34, and severe OSA was found to have 59.16 ± 22.15 events/hour. The study group's average age was 53.77 ± 7.19 out of 175 OSA patients. According to AHI, the BMI for mild OSA was 31.66 ± 8.32 kg/m, for moderate OSA, it was 30.52 ± 3.99 kg/m, and for severe OSA, it was 34.35 ± 8.22 kg/m. The average number of oxygen desaturation events and snoring duration were 25.20 ± 18.63 and 24.61 ± 28.53 min, respectively. BMI ( = 0.249, < 0.001), average oxygen saturation ( = -0.387, < 0.000), oxygen desaturation ( = 0.661, < 0.000), snoring time ( = 0.231, < 0.002), and the number of snores ( = 0.383, < 0.001) were the polysomnographic variables that showed significant correlations with AHI in the study group. In this study, a substantial prevalence of obesity and a high OSA frequency were found in men. Our research showed that individuals with obstructive sleep apnea experience nocturnal desaturations. Polysomnography is the primary test for early detection of this treatable condition.
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http://dx.doi.org/10.3390/jpm13060919 | DOI Listing |
Nat Sci Sleep
September 2025
Department of Respiratory Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Background: Recent research has increasingly underscored a significant correlation between gut microbiota and obstructive sleep apnea (OSA). Probiotics have emerged as promising adjunctive interventions for OSA. Metabolites and their related biochemical pathways have emerged as important contributors to the development of OSA.
View Article and Find Full Text PDFJ Pain Res
September 2025
Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People's Republic of China.
Purpose: Postoperative hyperalgesia (POH) is a common clinical phenomenon that will increase the experience of patients' pain. Previous studies have confirmed that surgical site, opioid analgesics, gender, and age were risk factors of POH. Limited research has been investigated to prove the association between obstructive sleep apnea (OSA) and POH.
View Article and Find Full Text PDFFront Physiol
August 2025
Department of Rehabilitation Medicine, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Objective: To explore the exercise capacity in obese patients with severe obstructive sleep apnea syndrome (OSAS) through cardiopulmonary exercise test (CPET).
Methods: In this cross-sectional study, patients with simple obesity (36 cases) and obese patients with severe OSAS (45 cases) admitted to the Department of Rehabilitation Medicine and the Department of General Practice of the Affiliated Wuxi People's Hospital of Nanjing Medical University from September 2019 to January 2024 were collected. Additionally, we included 33 patients (BMI<28 kg/m,AHI<5/hour) as a control group.
J Nephrol
September 2025
Department of Cardiovascular Sciences, University of Leicester, John Walls' Renal Unit, University Hospitals of Leicester NHS Trust, Leicester, UK.
Background: Individuals with kidney failure experience elevated cardiovascular risk, potentially worsened by the presence of sleep disordered breathing. Despite this association, prevalence of sleep apnoea, and evidence for effective treatments are poorly understood in people with kidney failure. This review examines sleep apnoea prevalence, types of sleep apnoea, and treatment interventions in people with kidney failure receiving dialysis.
View Article and Find Full Text PDFSci Rep
September 2025
College of First Clinical Medical, Shandong University of Traditional Chinese Medicine, Jinan, China.
Obstructive sleep apnea (OSA) is associated with metabolic disorders such as insulin resistance and liver fat accumulation. However, the specific mediating role of liver-related metabolic indicators in this association has not been fully studied. The purpose of this study was to investigate the relationship between Metabolic Score for Insulin Resistance (METS-IR) and OSA, focusing on the mediating effects of liver fat percentage (PLF) and hepatic steatosis index (HSI).
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