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Background: Computer-aided design and manufacturing (CAD/CAM) is widely used in clinical practice. This technology may change existing methods for mandibular fracture management.
Purpose: The purpose of this in-vitro study was to determine if the reduction for mandibular symphysis fracture can be performed without maxillomandibular fixation (MMF) using 3-dimensional (3D)-printed template.
Study Design, Setting, And Sample: This in-vitro study was designed as a proof-of-concept. The sample was composed of 20 existing pairs of intraoral scan and computed tomography (CT) data. A mandibular model stereolithography (STL) file was created by merging the STL file obtained for the bimaxillary dentitions with the CT DICOM file, and this was set as the original model. Using the original model, a STL file of a fracture model of the mandibular symphysis was created using CAD. A template similar to a wafer or an implant guide was manufactured to restore original occlusion, and the mandibular fracture model was reduced and fixed using the 3D-printed template and wire. This was set as the experimental group. The 3D coordinate system error was measured at 6 landmarks and statistically compared using scan data between models of the groups.
Predictor/exposure/independent Variables: Reduction techniques with MMF or without MMF using guide template for mandibular fracture model.
Main Outcome Variable(s): The 3D coordinate system error (mm).
Covariates: The position of landmarks.
Analyses: The Mann-Whitney U test, student's t-test, and the Kruskal-Wallis test were used to analyze the coordinate errors between the landmarks. A P value of < .05 was considered statistically significant.
Results: The 3D error value of the control and experimental group were 1.06 ± 0.63 mm (range: 0.11 to 2.92 mm) and 0.96 ± 0.48 mm (range: 0.2 to 2.95 mm), respectively. There was no statistical difference between the control and experimental group. There was a statistically significant difference in the lower 2 and lower 3 landmarks compared to the upper 1 (P = .001 and .000, respectively) before and after the reduction in the experimental group.
Conclusion And Relevance: This study demonstrates that the reduction using a 3D-printed guide template for the mandibular symphysis fracture could be possible even without the MMF.
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http://dx.doi.org/10.1016/j.joms.2023.05.002 | DOI Listing |
NIHR Open Res
September 2025
Department of Neurology, North Bristol NHS Trust, Westbury on Trym, England, UK.
Background: This study aimed to explore the barriers and facilitators of implementing rehabilitation interventions for visual field loss due to stroke.
Methods: The study was a qualitative exploration using one-to-one interviews coded using template analysis and the COM-B a-priori framework. Participants were five occupational therapists from hospital (n=4) and community (n=1) National Health Service (NHS) stroke care settings in England.
Nucleic Acids Res
September 2025
Expression génétique microbienne, UMR8261 CNRS, Université Paris Cité, Institut de Biologie Physico-Chimique, Paris 75005, France.
Targeted gene editing can be achieved using CRISPR-Cas9-assisted recombineering. However, high-efficiency editing requires careful optimization for each locus to be modified, which can be tedious and time-consuming. In this work, we developed a simple, fast and cheap method: Engineered Assembly of SYnthetic operons for targeted editing (EASY-edit) in Escherichia coli.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Percutaneous transthoracic lung biopsy (PTNB) guided by Computed Tomography (CT) greatly depends on the operators' skill for accuracy. This study aimed to evaluate whether three-dimensionally(3D) printed navigational templates for percutaneous transthoracic lung biopsy achieve diagnostic yield comparable to conventional computed tomography guidance.
Materials And Methods: Conducted from 1 November 2020, to 27 July 2023, this noninferiority randomized clinical trial included 159 patients with peripheral lung masses (≥30 mm).
Elife
September 2025
Center for Mind and Brain, University of California, Davis, Davis, United States.
Visual search relies on the ability to use information about the target in working memory to guide attention and make target-match decisions. The 'attentional' or 'target' template is thought to be encoded within an inferior frontal junction (IFJ)-visual attentional network. While this template typically contains veridical target features, behavioral studies have shown that target-associated information, such as statistically co-occurring object pairs, can also guide attention.
View Article and Find Full Text PDFMagn Reson Lett
May 2025
National Center for Magnetic Resonance in Wuhan, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, 430071, China.
Organic structure directing agents (OSDAs), such as tetrapropylammonium (TPA) cations, serve as crucial templates for the formation of zeolite frameworks. These organic molecules interact with inorganic species, guiding the assembly of the zeolite structure. In this study, we investigate the complex interplay between boron species and TPA cations during the crystallization of [B, Al]-ZSM-5 zeolites.
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