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Colonoscopy, as the golden standard for screening colon cancer and diseases, offers considerable benefits to patients. However, it also imposes challenges on diagnosis and potential surgery due to the narrow observation perspective and limited perception dimension. Dense depth estimation can overcome the above limitations and offer doctors straightforward 3D visual feedback. To this end, we propose a novel sparse-to-dense coarse-to-fine depth estimation solution for colonoscopic scenes based on the direct SLAM algorithm. The highlight of our solution is that we utilize the scattered 3D points obtained from SLAM to generate accurate and dense depth in full resolution. This is done by a deep learning (DL)-based depth completion network and a reconstruction system. The depth completion network effectively extracts texture, geometry, and structure features from sparse depth along with RGB data to recover the dense depth map. The reconstruction system further updates the dense depth map using a photometric error-based optimization and a mesh modeling approach to reconstruct a more accurate 3D model of colons with detailed surface texture. We show the effectiveness and accuracy of our depth estimation method on near photo-realistic challenging colon datasets. Experiments demonstrate that the strategy of sparse-to-dense coarse-to-fine can significantly improve the performance of depth estimation and smoothly fuse direct SLAM and DL-based depth estimation into a complete dense reconstruction system.
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http://dx.doi.org/10.1016/j.compbiomed.2023.106983 | DOI Listing |
Adv Sci (Weinh)
September 2025
Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, 200031, China.
Maintaining cellular ploidy is critical for normal physiological processes, although gains in ploidy are frequently observed during development, tissue regeneration, and metabolism, and potentially contribute to aneuploidy, thereby promoting tumor evolution. Although numerous computational tools have been developed to estimate cellular ploidy from whole-genome sequencing (WGS) data at bulk or single-cell resolution, to the knowledge, no systematic comparison of their performance has been conducted. Here, a benchmarking study is presented of 11 methods for bulk WGS and 8 methods for single-cell WGS data, utilizing both experimental and simulated datasets derived from diploid cells mixed with aneuploid or polyploid cells.
View Article and Find Full Text PDFNew Phytol
September 2025
Environment and Natural Resources Institute, University of Alaska Anchorage, Anchorage, AK, 99508, USA.
Snow is an important insulator of Arctic soils during winter and may be a source of soil moisture in summer. Changes in snow depth are likely to affect fine root growth and mortality via changes in soil temperature, moisture, and/or nutrient availability, which could alter aboveground growth and reproduction of Arctic vegetation. We explored fine root dynamics at three contrasting treelines in northwest Alaska.
View Article and Find Full Text PDFClin Oral Investig
September 2025
Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technology Sciences, SIMATS, Saveetha University, Chennai, Tamil Nadu, India.
Objectives: This study aims to assess periodontal and biochemical parameters and evaluate the salivary Protectin D1 levels in periodontitis patients with and without metabolic syndrome after non-surgical periodontal therapy.
Materials And Methods: Forty patients were categorized into two groups: 20 patients in Group P (systemically healthy patients with stage II/III grade B periodontitis) and 20 patients in Group P+MS (patients with stage II/III grade B periodontitis and metabolic syndrome). Parameters including age, gender, height, weight, body mass index, waist circumference, socio-economic status, oral hygiene index (OHI), modified gingival index (MGI), probing pocket depth, clinical attachment levels, fasting blood glucose, HDL-c, total triglycerides, and blood pressure were recorded.
Spectrochim Acta A Mol Biomol Spectrosc
August 2025
State Key Laboratory for Safe Mining of Deep Coal Resources and Environment Protection, Anhui University of Science and Technology, Huainan 232001, China; School of Spatial Informatics and Geomatics Engineering, Anhui University of Science and Technology, Huainan 232001, China. Electronic address: c
Conventional methods for soil sampling and soil water content (SWC) measurement are often labor-intensive and time-consuming. The Pedo-transfer function (PTF) integrating soil spectroscopy with soil physicochemical properties provides a more efficient approach for SWC estimation. However, existing studies highlight regional limitations in the accuracy of PTFs across diverse geographical regions.
View Article and Find Full Text PDFDNA abnormalities characterized by cytogenetic imaging at the single cell resolution, i.e. karyotyping, have long served as cancer diagnostic and prognostic biomarkers.
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