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An advanced optical terahertz (THz) fingerprint sensor based on coherent perfect absorption (CPA) is proposed. Based on a one-dimensional layered photonic structure, the sensor contains a cavity that is developed for THz fingerprint measurement. Utilizing the magneto-optical effect of magnetized InSb, CPA is excited in the structure of the sensor. Taking α-lactose as exemplar material, this numerical simulation is integrated with a Drude-Lorentz model. The transfer matrix method (TMM) is used to calculate the sensitivity (), linear range (LR), quality (), the figure of merit (FOM*), and detection limit (DL) theoretically. Employing the amplitude modulation detection method, the qualitative and quantitative analysis of the α-lactose thickness of 0-0.5 μm could be realized. Because of the fragility of CPA, the is 0.78255 μm, the value of average is up to 8019.2, the value of average FOM* is 13 234.4 (THz μm), and the lower DL is 4.21 × 10. Moreover, the evolutions of ensemble-averaged absorption in the vicinity of the absorption peaks for different types of disorder effects are considered, which will be considered in the fabrication of sensors.
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http://dx.doi.org/10.1039/d3cp00592e | DOI Listing |
PLoS One
September 2025
School of Medical Engineering, Xinxiang Medical University, Xinxiang, China.
Computer-aided diagnostic (CAD) systems for color fundus images play a critical role in the early detection of fundus diseases, including diabetes, hypertension, and cerebrovascular disorders. Although deep learning has substantially advanced automatic segmentation techniques in this field, several challenges persist, such as limited labeled datasets, significant structural variations in blood vessels, and persistent dataset discrepancies, which continue to hinder progress. These challenges lead to inconsistent segmentation performance, particularly for small vessels and branch regions.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Centre for Engineering Biology, Institute of Quantitative Biology, Biochemistry and Biotechnology, School of Biological Sciences, University of Edinburgh;
Recent advances have enabled the Protein synthesis Using Recombinant Elements (PURE) cell-free system to be produced in individual laboratories economically and with reduced labor burden. However, the preparation of the 36 protein components and ribosome, which make up PURE, is still a complex undertaking, with much scope for variation and error. We present a detailed and updated procedure to manufacture PURE based on the recently published OnePot protocol, which involves regulating a number of key steps, in particular, the inoculation of cultures using optical density (OD)-normalized glycerol stocks, careful monitoring of cell growth, and controlling final glycerol concentrations.
View Article and Find Full Text PDFVestn Oftalmol
September 2025
Krasnov Research Institute of Eye Disease, Moscow, Russia.
Phacoemulsification with intraocular lens (IOL) implantation has become the standard method for cataract extraction regardless of its etiology. In modern phaco surgery, implantation of multifocal IOLs is considered the most advanced method for correcting aphakia following lens extraction. The wide range of available multifocal IOLs is promoting the ongoing discussion regarding the advantages of each type, as well as potential strategies for optimizing surgical outcomes.
View Article and Find Full Text PDFVestn Oftalmol
September 2025
OOO Diagnosticheskij tsentr Zreniye, Saint Petersburg, Russia.
Objective: This study evaluated the effect of sequential therapy with different dosages of Mexidol on the stabilization of glaucomatous optic neuropathy (GON) in patients with primary open-angle glaucoma (POAG).
Material And Methods: The study included 80 patients (160 eyes) with stage II and III POAG, randomized into three groups comparable by age, gender, and distribution of glaucoma stage. All patients received sequential therapy with Mexidol (14 days parenterally followed by 90 days orally).
Vestn Oftalmol
September 2025
Multidisciplinary Medical Center of Svyatoslav Fedorov Foundation for the Promotion of Advanced Medical Technologies, Moscow, Russia.
Unlabelled: Diffuse lamellar keratitis (DLK) is a known complication of lamellar corneal surgery. The underlying mechanism of the cellular response in DLK is well described. There are two clinical forms - sporadic and cluster - each largely influenced by surgical triggers.
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