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Terahertz (THz) radiation has the capability to combine spectroscopy and imaging in a single system. The resulting hyperspectral images can reveal concealed objects and identify materials by means of characteristic spectral features. For security applications, THz is attractive for its non-contact and non-destructive measurement capabilities. For such applications, objects may be too absorbing for transmission measurements, or only one side of an object may be accessible, necessitating a reflection measurement configuration. This work details the development and demonstration of a compact fiber-coupled hyperspectral imaging reflection system suited to field use for security and industrial applications. The system uses beam steering to measure objects of up to 150 mm diameter with a depth range of up to 255 mm, allowing for 3-dimensional mapping of objects, while simultaneously acquiring spectral data. Spectral information between 0.2-1.8 THz is extracted from a hyperspectral image and used to identify lactose, tartaric acid, and 4-aminobenzoic acid in high and low humidity environments.
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http://dx.doi.org/10.1364/OE.485573 | DOI Listing |
Light Sci Appl
September 2025
Key Lab of Environmental Optics & Technology, Anhui Institute of Optics and Fine Mechanics, Hefei Institutes of Physical Science, Chinese Academy of Sciences, 230031, Hefei, China.
Marine vessels play a vital role in the global economy; however, their negative impact on the marine atmospheric environment is a growing concern. Quantifying marine vessel emissions is an essential prerequisite for controlling these emissions and improving the marine atmospheric environment. Optical imaging remote sensing is a vital technique for quantifying marine vessel emissions.
View Article and Find Full Text PDFSci Total Environ
September 2025
University Hohenheim, Department of Process Analytics and Cereal Science, Stuttgart, 70599, Germany.
Per- and polyfluoroalkyl substances (PFAS) are persistent organic pollutants with increasing prevalence in agricultural soils, primarily introduced through biosolid application, wastewater irrigation, and atmospheric deposition. This review provides a meta-analysis of terminologies across 145 peer-reviewed studies, identifying inconsistency in the classification of PFAS subgroups-such as "long-chain vs. short-chain," "precursors," and "emerging PFAS"-which hinders regulatory harmonization and model calibration.
View Article and Find Full Text PDFCompr Rev Food Sci Food Saf
September 2025
Agricultural Product Processing and Storage Lab, School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu, China.
Fruit and fruit-based products are a valuable source of essential nutrients, critical for food security, and drive economic productivity with minimal inputs. The significant rise in global demand for high-quality imported fruit and fruit-based products reflects a shift in consumer awareness and interest in the products origin and potential health-promoting bioactive compounds. Analytical techniques such as liquid chromatography, gas chromatography, inductively coupled plasma techniques, isotope-ratio mass spectrometry (IRMS), near infrared (NIR) spectroscopy, visible near infrared (VIS-NIR) spectroscopy, hyperspectral imaging (HSI), mid-infrared (MIR) spectroscopy, Raman spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, fluorescence spectroscopy, terahertz spectroscopy, dielectric spectroscopy, electronic nose (e-nose), and electronic tongue (e-tongue) coupled with supervised and unsupervised chemometrics can be employed for traceability, authentication, and bioactive profiling of fruit and fruit-based products.
View Article and Find Full Text PDFEur J Pharm Biopharm
September 2025
Research Center Pharmaceutical Engineering GmbH, Inffeldgasse 13, 8010 Graz, Austria; University of Graz, Institute of Pharmaceutical Sciences, Department of Pharmaceutical, Technology and Biopharmacy, Graz, Austria. Electronic address:
Lipid-based formulations have been successfully applied to improve the aqueous solubility of active pharmaceutical ingredients (APIs), however, with the bottleneck of limited wettability of the system. In this study, a lipid-based system was developed using polyglycerol ester of fatty acids (PGFA) as the main component and hexaglycerol (PG6) as a wetting agent. Felodipine, a BCS class II compound was selected as a model API.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Laser Biomedical Research Center, G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology.
We present multimodal confocal Raman micro-spectroscopy (RS) and tomographic phase microscopy (TPM) for quick morpho-chemical phenotyping of human breast cancer cells (MDA-MB-231). Leveraging the non-perturbative nature of these advanced microscopy techniques, we captured detailed morpho-molecular data from living, label-free cells in their native physiological environment. Human bias-free data processing pipelines were developed to analyze hyperspectral Raman images (spanning Raman modes from 600 cm to 1800 cm, which uniquely characterize a wide range of molecular bonds and subcellular structures), as well as morphological data from three-dimensional refractive index tomograms (providing measurements of cell volume, surface area, footprint, and sphericity at nanometer resolution, alongside dry mass and density).
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