Efficient mitigation of emerging antibiotics residues from water matrix: Integrated approaches and sustainable technologies.

The prevalence of antibiotic traces in the aquatic matrices is a concern due to the emanation of antibiotic resistance which requires a multifaceted approach. One of the potential sources is the wastewater treatment plants with a lack of advance infrastructure leading to the dissemination of contaminants. Continuous advancements in economic globalization have facilitated the application of several conventional, advanced, and hybrid techniques for the mitigation of rising antibiotic traces in the aquatic matrices that have been thoroughly scrutinized in the current paper. Although the implementation of existing mitigation techniques is associated with several limiting factors and barriers which require further research to enhance their removal efficiency. The review further summarizes the application of the microbial processes to combat antibiotic persistence in wastewater establishing a sustainable approach. However, hybrid technologies are considered as most efficient and environmental-benign due to their higher removal efficacy, energy-efficiency, and cost-effectiveness. A brief elucidation has been provided for the mechanism responsible for lowering antibiotic concentration in wastewater through biodegradation and biotransformation. Overall, the current review presents a comprehensive approach for antibiotic mitigation using existing methods however, policies and measures should be implemented for continuous monitoring and surveillance of antibiotic persistence in aquatic matrices to reduce their potential risk to humans and the environment.