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Background: Laughter has been reported to have various health benefits. However, data on the long-term effects of laughter interventions on diabetes are limited. This study aimed to investigate whether laughter yoga can improve glycemic control among individuals with type 2 diabetes.
Methods: In a single-center, randomized controlled trial, 42 participants with type 2 diabetes were randomly assigned to either the intervention or the control group. The intervention consisted of a 12-week laughter yoga program. Hemoglobin A1c (HbA1c), body weight, waist circumference, psychological factors, and sleep duration were evaluated at baseline and week 12.
Results: Intention-to-treat analysis showed that participants in the laughter yoga group experienced significant improvements in HbA1c levels (between-group difference: -0.31%; 95% CI -0.54, -0.09) and positive affect scores (between-group difference: 0.62 points; 95% CI 0.003, 1.23). Sleep duration tended to increase in the laughter yoga group with a between-group difference of 0.4 hours (95% CI -0.05, 0.86; = 0.080). The mean attendance rate for laughter yoga program was high (92.9%).
Conclusions: A 12-week laughter yoga program is feasible for individuals with type 2 diabetes and improves glycemic control. These findings suggest that having fun could be a self-care intervention. Further studies with larger numbers of participants are warranted to better evaluate the effects of laughter yoga.
Clinical Trial Registration: http://www.chinadrugtrials.org.cn, identifier UMIN000047164.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10102335 | PMC |
http://dx.doi.org/10.3389/fendo.2023.1148468 | DOI Listing |
J Clin Med
August 2025
Department of Medical-Surgical Nursing, Nursing School of Lisbon (ESEL), 1600-190 Lisbon, Portugal.
: Family caregivers in palliative care often face complex physical, emotional, and logistical challenges, which can result in a significant caregiving burden. Dyadic interventions-designed to support both the patient and the caregiver simultaneously-have emerged as a promising holistic approach to enhancing well-being and quality of life. This systematic review aimed to evaluate the effects of dyadic support interventions in reducing caregiver burden among middle-aged and older adults receiving palliative care.
View Article and Find Full Text PDFJMIR Aging
August 2025
Care & Technology Lab, Faculty 3: Health, Medical & Life Sciences, Furtwangen University, Furtwangen, Germany.
Background: Approximately 20% of the global population is affected by mild cognitive impairment (MCI), with around 15% progressing to dementia within 2 years. Touch-based multimedia applications can support cognitive, social, and physical functioning, potentially enhancing daily life and strengthening caregiver-patient relationships through shared engagement. Although interest in dyadic, technology-assisted interventions is increasing, empirical evidence on their feasibility and acceptability in home-based settings remains scarce.
View Article and Find Full Text PDFNurse Educ Pract
August 2025
Bursa Uludag University Faculty of Health Sciences, Department of Internal Medicine Nursing, Nilüfer, Bursa 16059, Türkiye. Electronic address:
Aim: To evaluate the effectiveness of laughter-based interventions across psychological, physiological and educational outcomes in nursing students.
Background: Nursing education may involve educational, emotional and clinical demands that could impact students' well-being and academic success. Laughter-based interventions may help to reduce these challenges.
High-dose transcranial magnetic stimulation-induced excessive laughter in a 6-year-old autistic male. We hypothesized that this phenomenon reflected prefrontal disinhibition or exaggerated emotional response. This case emphasizes the necessity for modified treatment protocols with concurrent psychiatric assessment, emotional evaluation, and neurophysiological monitoring when encountering such adverse effects during neuromodulation therapy.
View Article and Find Full Text PDFNeuropsychopharmacol Rep
September 2025
Aliasghar Clinical Research Development Center, Aliasghar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Introduction: Atomoxetine, a selective norepinephrine reuptake inhibitor (NRI), is commonly prescribed for attention-deficit/hyperactivity disorder (ADHD) and has shown effectiveness in children with autism spectrum disorder (ASD). Although mood disturbances and psychiatric symptoms are recognized side effects, pathological laughter has not been previously reported.
Case Presentation: We present the case of a 6-year-old boy diagnosed with both ASD and ADHD who developed sudden, uncontrollable episodes of pathological laughter after beginning low-dose atomoxetine (5 mg/day, ~0.