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The potential for complex systems to exhibit tipping points in which an equilibrium state undergoes a sudden and often irreversible shift is well established, but prediction of these events using standard forecast modelling techniques is quite difficult. This has led to the development of an alternative suite of methods that seek to identify signatures of critical phenomena in data, which are expected to occur in advance of many classes of dynamical bifurcation. Crucially, the manifestations of these critical phenomena are generic across a variety of systems, meaning that data-intensive deep learning methods can be trained on (abundant) synthetic data and plausibly prove effective when transferred to (more limited) empirical datasets. This paper provides a proof of concept for this approach as applied to lattice phase transitions: a deep neural network trained exclusively on two-dimensional Ising model phase transitions is tested on a number of real and simulated climate systems with considerable success. Its accuracy frequently surpasses that of conventional statistical indicators, with performance shown to be consistently improved by the inclusion of spatial indicators. Tools such as this may offer valuable insight into climate tipping events, as remote sensing measurements provide increasingly abundant data on complex geospatially resolved Earth systems.
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http://dx.doi.org/10.1098/rsif.2022.0562 | DOI Listing |
J Agric Food Chem
September 2025
Department of Applied Chemistry, College of Science, China Agriculture University, Beijing 100091, China.
l-glufosinate has garnered increasing attention as an ideal herbicide for weed control in agriculture. However, the underlying racemization process of l-glufosinate in the aqueous phase remains unclear. In this work, we elucidated the racemization mechanisms through heating reactions and theoretical calculations.
View Article and Find Full Text PDFMacromol Biosci
September 2025
Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Conventional gelatin's gel-to-sol transition upon heating restricts its utility in biomedical applications that benefit from a gel state at physiological temperatures such as Pluronic F127 and poly(NIPAAm). Herein, we present "rev-Gelatin", a gelatin engineered with reverse thermo-responsive properties that undergoes a sol-to-gel transition as temperature rises from ambient to body temperature. Inspired by the phase dynamics of common materials like candy and ice cubes, whose surfaces soften or partially melt under warming, facilitating inter-object adhesion- rev-Gelatin leverages this concept to achieve fluidity at room temperature for easy injectability.
View Article and Find Full Text PDFJ Anim Sci
September 2025
Department of Animal Sciences, Laval University, Québec, QC G1V 0A6, Canada.
In pig production, weaning is a critical period where piglets face several environmental stressors. This transition leads to a significant growth reduction and can result in digestive disorders, including diarrhea. To formulate a feed that meets zinc (Zn) and copper (Cu) requirements during the weaning period while minimizing their release into the environment, it became evident that a more bioavailable micro-mineral supplement is necessary.
View Article and Find Full Text PDFJ Phys Chem A
September 2025
Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
The gas-phase structures of dibenzo-24-crown-8 (DB24C8) and dinaphtho-24-crown-8 (DN24C8) complexes with divalent metal ions (Mg, Ca, Sr, Ba, Fe, Ni, and Zn) were investigated by cryogenic ion mobility-mass spectrometry (IM-MS) in combination with density functional theory calculations. Several complexes, particularly those of DN24C8, exhibited multiple coexisting conformers. DFT-optimized structures were classified based on the relative orientation of the two aromatic rings in the crown ether.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
September 2025
Forefront Research Center, Graduate School of Science, The University of Osaka, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan.
This study explores the computational isolation of prostaglandin (PG) isomers, specifically PG E (PGE) and D (PGD), to enhance method development efficiency and provide insights into their retention behavior during supercritical fluid extraction (SFE) combined with supercritical fluid chromatography (SFC)-tandem mass spectrometry (MS/MS). Although PGE and PGD are positional isomers that yield identical product ions in MS/MS, they serve distinct biological roles. This research illustrates the efficacy of selected reaction monitoring (SRM)-based techniques for differentiating coeluting isomers.
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