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What Is Already Known About This Topic?: Tuberculosis (TB) is a multisystem disease that might affect any organ. Currently, the National TB Program (NTP) issued by the State Council of China, only covers pulmonary tuberculosis (PTB), and the status of extrapulmonary tuberculosis (EPTB) remains unclear nationwide.
What Is Added By This Report?: The survey conducted by China CDC reported that there were no specific health facilities responsible for diagnosis, treatment and management of EPTB in China, while more than half of counties thought it should be included into NTP.
What Are The Implications For Public Health Practice?: China should include EPTB into NTP to achieve the target of End-TB strategy, a world free of TB. Zero deaths, disease and suffering due to TB.
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http://dx.doi.org/10.46234/ccdcw2023.032 | DOI Listing |
Cureus
August 2025
Respiratory Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Tuberculosis (TB) is a multisystem infectious disease with both pulmonary and extrapulmonary manifestations. TB can also induce a hypercoagulable state, setting off a cascade of changes in the body, including systemic inflammation, endothelial dysfunction, and abnormalities in the coagulation and fibrinolytic pathways. Collectively, these factors significantly increase the risk of venous thromboembolism, such as deep vein thrombosis and pulmonary embolism.
View Article and Find Full Text PDFNed Tijdschr Tandheelkd
September 2025
the Department of Internal Medicine, University Medical Center Groningen (UMCG).
A 27-year-old man from Ethiopia had undergone an extraction of a molar in Libya ten months earlier, after which a submental swelling developed. For that reason, an oral and maxillofacial surgery department was consulted. Clinical examination showed a tender, firm-to-the-touch, non-mobile swelling with central ulceration.
View Article and Find Full Text PDFActa Ortop Mex
September 2025
Universidad de Manizales. Colombia.
Articular tuberculosis is a rare condition, with extrapulmonary presentations most commonly appearing in joints such as the hip or knee. It is usually associated with conditions like immunosuppression or a history of pulmonary tuberculosis. Diagnosis involves imaging or pathology, and treatment typically involves surgical intervention along with medication.
View Article and Find Full Text PDFInt J Infect Dis
September 2025
SAMRC Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa; Department of Microbiology and Biochemistry, Faculty of Natural and Agricultural Sciences, University of the Free State, Bloemfontei
Background: Mycobacterium simiae is a slow-growing environmental nontuberculous mycobacterium (NTM), commonly isolated from soil and water. M. simiae is not known to transmit zoonotically or via human-to-human contact; infection is presumed to occur through direct environmental exposure.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Tuberculosis, Guiyang Public Health Clinical Center, Guiyang, Guizhou Province, China.
Rationale: We report an extremely rare case in which delayed diagnosis and treatment of Mycobacterium tuberculosis infection primarily involving the subcutaneous tissues of an extremity led to hematogenous dissemination of the infection and subsequent deterioration of the patient.
Patient Concerns: An 82-year-old man presented to our hospital with a painful mass on the right ankle for over a year, as well as persistent fever and shortness of breath for >14 days. He received piperacillin/tazobactam followed by meropenem, which failed to decrease his peak temperature.