Hemodynamic Evaluation of a Centrifugal Left Atrial Decompression Pump for Heart Failure with Preserved Ejection Fraction.

Bioengineering (Basel)

Department of Cardiovascular and Thoracic Surgery, Institute of Cardiology, Pitié Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne University, F-75013 Paris, France.

Published: March 2023


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Article Abstract

This article discusses a new continuous flow mini pump that has been developed to improve symptoms and prognosis in patients with Heart Failure with Preserved Ejection Fraction (HFpEF), for which there are currently no established treatments. The pump is designed to discharge a reduced percentage of blood volume from the left atrium to the subclavian artery, clamped at the bifurcation with the aortic arch. The overall specifications, design parameters, and hemodynamics of this new device are discussed, along with data from in vitro circulation loop tests and numerical simulations. The article also compares the results for two configurations of the pump with respect to key indicators of hemocompatibility used in blood pump development.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044772PMC
http://dx.doi.org/10.3390/bioengineering10030366DOI Listing

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