Lung resistance - but not compliance - impairs P0.1 and maximal inspiratory pressure measurements.

Introduction: Bedside tools have been developed to assess inspiratory muscle function and inspiratory drive for patients under invasive mechanical ventilation. Occlusion maneuvers are currently considered but their pitfalls remain underexplored. We aimed to assess the impact of respiratory system compliance and resistance on P0.

Improving the hemocompatibility of centrifugal mechanical circulatory support devices at low flow rates.

Background: An innovative solution has been recently proposed for the treatment of heart failure with preserved ejection fraction (HFpEF), using a centrifugal mechanical circulatory support (MCS) device. We sought firstly to assess the hemocompatibility of the proposed device. HFpEF treatment requires the blood pump to operate at low blood flow rate (0.

Numerical Assessment of the Hydrodynamic Behavior of a Volute Centrifugal Pump Handling Emulsion.

Although emulsion pumping is a subject of growing interest, a detailed analysis of the fluid dynamic phenomena occurring inside these machines is still lacking. Several computational investigations have been conducted to study centrifugal pumps carrying emulsion by analyzing their overall performance, but no studies involved the rheological behavior of such fluids. The purpose of this study is to perform a computational analysis of the performance and flow characteristics of a centrifugal pump with volute handling emulsions and oil-water mixtures at different water cuts modeled as a shear-thinning non-Newtonian fluid.

The evolution of long-term pediatric ventricular assistance devices: a critical review.

: The gap between the number of heart failure patients and the number of potential heart donors has never been larger than today, especially among the pediatric population. The use of mechanical circulatory support is seen as a potential alternative for clinicians to treat more patients. This treatment has proven its efficiency on short-term use.