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We report a case of hypothermic death that resulted from extreme freezing, with characteristic postmortem computed tomography (PMCT) findings. A 75-year-old man died in a deeply frozen state. In PMCT, there was a lack of increase in the bilateral lung-field attenuation. Urinary retention, with a hypodense area of frozen urine, was observed in the bladder. Changes that appeared to involve the crystallization of serum in frozen blood were observed in the aorta. Based on the scene and his circumstances, it was speculated that he died of hypothermia. Present case and our review revealed that although PMCT findings from hypothermic death that resulted from deep freezing are very rare, the characteristic PMCT findings may help determine the cause of death.
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http://dx.doi.org/10.1016/j.radcr.2023.01.007 | DOI Listing |
Medicine (Baltimore)
September 2025
Department of Emergency Medicine, Ajou University School of Medicine, Suwon, South Korea.
This study aimed to investigate the clinical course of brain death donors and admitted through the emergency department before organ procurement and early outcomes of kidney transplantation. We retrospectively reviewed the medical records of patients who visited a single tertiary emergency department with the final diagnosis of brain death and donor procurement between January 2013 and January 2022. Donors were categorized into 3 groups: brain hemorrhage, hanging, and other medical causes.
View Article and Find Full Text PDFJ Cardiovasc Transl Res
September 2025
Department of Cardiac Surgery, University Hospital Halle (Saale), University of Halle, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.
We compared the effects of ex-vivo machine perfusion (EVMP) of hearts donated after circulatory death (DCD) with the single-shot solutions HTK-N and Del Nido cardioplegia (DNC) on left-ventricular (LV) contractility and myocardial microcirculation. In a DCD pig model, hearts were maintained by EVMP with hypothermic, oxygenated HTK-N (DCD-HTK-N; N = 8) or DNC (DCD-DNC; N = 8) followed by reperfusion with blood, including assessment of contractility and microcirculation with Laser-Doppler-Flow (LDF). We performed transcriptomics using microarrays.
View Article and Find Full Text PDFJAMIA Open
October 2025
Fetal-Neonatal Neuroimaging Developmental Science Center, Division of Newborn Medicine, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, United States.
Objectives: To develop a data harmonization framework for neonatal hypoxic-ischemic encephalopathy (HIE) studies and demonstrate its suitability for prognostic biomarker development.
Materials And Methods: Variables were first categorized by chronological stages and then by medical topics. We created a dictionary to harmonize variable names and value coding.
Baichuan Baile (BCBL) is a novel formula that incorporates three herbs and a single food additive, all of which are widely used in ordinary or functional foods. It is a promising dietary supplement for the treatment of depression based on TCM principles and nutritional assessments. Our study was designed to explore BCBL's antidepressant-like effects and elucidate its underlying mechanisms.
View Article and Find Full Text PDFAnn Surg
September 2025
Department of Hepatobiliary and Pancreas Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Objective: The aim of this study was to investigate the safety and outcomes of radical resection combined with in vivo hypothermic perfusion and intestinal auto-transplantation (IATx) for tumors invading the mesenteric root vascular system.
Background: Radical resection combined with IATx is safe and effective for mesenteric root tumors invading the vascular system. However, classic IATx procedures require removing the mesenteric root tumor as well as the small intestine and ascending colon for ex vivo hypothermic perfusion.