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Polyps in the colon are widely known cancer precursors identified by colonoscopy. Whilst most polyps are benign, the polyp's number, size and surface structure are linked to the risk of colon cancer. Several methods have been developed to automate polyp detection and segmentation. However, the main issue is that they are not tested rigorously on a large multicentre purpose-built dataset, one reason being the lack of a comprehensive public dataset. As a result, the developed methods may not generalise to different population datasets. To this extent, we have curated a dataset from six unique centres incorporating more than 300 patients. The dataset includes both single frame and sequence data with 3762 annotated polyp labels with precise delineation of polyp boundaries verified by six senior gastroenterologists. To our knowledge, this is the most comprehensive detection and pixel-level segmentation dataset (referred to as PolypGen) curated by a team of computational scientists and expert gastroenterologists. The paper provides insight into data construction and annotation strategies, quality assurance, and technical validation.
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http://dx.doi.org/10.1038/s41597-023-01981-y | DOI Listing |
BMJ Open Gastroenterol
September 2025
Manchester University NHS Foundation Trust, Manchester, UK.
Objective: People with cystic fibrosis (pwCF) are at significantly increased risk of colorectal cancer (CRC), prompting international recommendations for earlier screening with colonoscopy. The utility of faecal immunochemical testing (FIT) as a screening adjunct in pwCF remains unclear. This study evaluates FIT's diagnostic performance and uptake within a CRC screening programme in a UK CF centre.
View Article and Find Full Text PDFGastroenterol Hepatol
September 2025
Department of Gastroenterology, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), University of Barcelona. Barcelona, Catalonia, Spain. Electronic address:
Objective: The primary goal of a public health system is to ensure universal access to high-quality medical care. However, disparities in health outcomes have been observed across socio-demographic groups, some of them potentially related to their geographical location. To assess territorial equity, the Catalan Colorectal Cancer Screening Program was used, focusing on the adenoma detection rate (ADR) endoscopists.
View Article and Find Full Text PDFAnesth Analg
September 2025
Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Khirurgiia (Mosk)
September 2025
National Medical Research Center of Oncology, Rostov-on-Don, Russia.
Objective: To study the results of treatment of cancer in tubular villous adenomas.
Material And Methods: A retrospective analysis included 51 patients with cTis-T1N0M0 between 02.2019 and 09.
Medicine (Baltimore)
September 2025
Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China.
To observe the specific changes of auricular points in patients with colorectal polyps (CPs) by auricular assessment. To summarize the clusters of auricular point-specific changes in patients with CPs, and to inform further research into auricular point assisted diagnosis of CPs. A total of 300 participants, with 150 having CPs and 150 having no CPs, were recruited for this case-control study.
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