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Purpose: The purpose of this study was to investigate associations between digital urine color and paper urine color with other urine indices to assess hydration status.
Methods: Twelve male subjects (mean ± standard deviation; age, 26 ± 8 years; body mass, 57.8 ± 5.3 kg; height, 177.5 ± 8.9 cm; VO, 57.8 ± 5.8 ml·kg·min) performed four exercise trials in the heat. Before and following exercise trials, subjects provide urine samples. Urine samples were measured using a digital urine color chart on a portable device screen. Urine samples were also assessed with urine specific gravity (USG), urine osmolality (UOsmo), and a validated paper urine color chart.
Results: There were extremely large associations found between digital urine color and paper urine color (r = 0.926, p < 0.001). Correlation coefficients showing associations with USG and UOsmo were similar between digital urine color (USG, r = 0.695, p < 0.001; UOsmo, r = 0.555, p < 0.001) and paper urine color (USG, r = 0.713, p < 0.001; UOsmo, r = 0.570, p < 0.001). Bland-Altman analysis indicated that no proportional bias was observed between digital and paper urine colors (bias, - 0.148; SD of bias, 0.492; 95% LOA, - 1.11, 0.817; p = 0.094).
Conclusions: Strong associations were found between digital and paper urine colors with no proportional bias. Furthermore, the degree of associations with USG and UOsmo was similar between digital and paper urine color. These results indicate that digital urine color is a useful tool to assess hydration status and this method could be used as an alternative method to using paper urine color.
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http://dx.doi.org/10.1007/s00394-022-03037-0 | DOI Listing |
Medicine (Baltimore)
September 2025
Nutrition Department, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, China.
Rationale: Extracorporeal membrane oxygenation (ECMO) is a life-support technology for refractory cardiac arrest, but the massive blood transfusions required during treatment significantly increase the risk of transfusion-related infections. Hepatitis E virus (HEV) - traditionally linked to fecal-oral transmission - is increasingly recognized as a transfusion-transmitted pathogen, especially in emergency settings where urgent blood product infusion is common and routine HEV screening in blood banks is often lacking. However, nursing strategies for managing acute HEV infection after ECMO remain poorly defined, highlighting the need to address this clinical gap.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Emergency Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Red yeast rice (RYR), a commonly used supplement with statin-like properties, is generally considered safe but may cause severe adverse effects such as rhabdomyolysis. We report a rare case of severe RYR-induced rhabdomyolysis complicated by acute kidney injury (AKI) and respiratory failure, with diaphragmatic dysfunction as a key contributing factor. A 78-year-old woman developed progressive proximal muscle weakness, dyspnea, and tea-colored urine after taking RYR (2 g/day) for 1 month.
View Article and Find Full Text PDFCureus
August 2025
Department of Obstetrics and Gynecology, Ministry of National Guard Health Affairs, Riyadh, SAU.
This case report discusses the overall care of a female patient with nephrotic syndrome secondary to non-pre-eclampsia-related hypertension in pregnancy, emphasizing the challenges and multidisciplinary treatment needed for desired results. The case presented here involves a 32-year-old pregnant woman with a history of unexplained primary infertility who conceived through in vitro fertilization (IVF). At 26 weeks and three days of gestation, she presented with symptoms suggestive of nephrotic syndrome, including lower limb swelling, facial puffiness, oliguria, and dark-colored urine.
View Article and Find Full Text PDFGels
August 2025
College of Textile and Clothing Engineering, Soochow University, Suzhou 215021, China.
Urine pH serves as an indicator of systemic acid-base balance and helps detect early-stage urinary and renal disorders. However, conventional monitoring methods rely on instruments or manual procedures, limiting their use among vulnerable groups such as infants and bedridden elderly individuals. In this study, a pH-responsive smart hydrogel was developed and integrated into diapers to enable real-time, equipment-free, and visually interpretable urine pH monitoring.
View Article and Find Full Text PDFAntibiotics (Basel)
July 2025
Departmental Faculty of Medicine, Unicamillus-Saint Camillus International University of Health and Medical Sciences, 00131 Rome, Italy.
Urine microbial analysis is a frequently requested test that is often associated with contamination during specimen collection or storage, which leads to false-positive diagnoses and delayed reporting. In the era of digitalization, machine learning (ML) can serve as a valuable tool to support clinical decision-making. This study investigates the application of a simple artificial neural network (ANN) to pre-identify negative and contaminated (false-positive) specimens.
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