98%
921
2 minutes
20
The fabrication of green optical waveguides based on cellulose and spider silk might allow the processing of novel biocompatible materials. Regenerated cellulose fibers are used as the core and recombinantly produced spider silk proteins eADF4(C16) as the cladding material. A detected delamination between core and cladding could be circumvented by using a modified spider silk protein with a cellulose-binding domain-enduring permanent adhesion between the cellulose core and the spider silk cladding. The applied spider silk materials were characterized optically, and the theoretical maximum data rate was determined. The results show optical waveguide structures promising for medical applications, for example, in the future.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844472 | PMC |
http://dx.doi.org/10.3390/biomimetics8010037 | DOI Listing |
Langmuir
September 2025
Department of Light Chemical Engineering, School of Textiles Science and Engineering; Key Laboratory of Special Protective, Ministry of Education; Jiangnan University, Wuxi 214122, P. R. China.
Polymerizable deep eutectic solvents (PDES) have recently emerged as a class of solvent-free ionically conductive elastomers and are considered among the most feasible candidates for next-generation ionotronic devices. However, the fundamental challenge persists in synergistically combining high mechanical strength, robust adhesion, reliable self-healing capacity, and effective antimicrobial performance within a unified material system capable of fulfilling the rigorous operational demands of next-generation ionotronic devices across multifunctional applications. Inspired by the hierarchical structure of spider silk, HCAG eutectogels composed of acrylic acid (AA), 2-hydroxyethyl acrylate (HEA), and choline chloride (ChCl) were successfully synthesized via a one-step photopolymerization method.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Department of Protein Science, Division of Protein Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, AlbaNova University Center, Stockholm, Sweden. Electronic address:
This paper presents the generation and evaluation of a novel potential drug delivery platform for biologics, based on recombinant spider silk. Targeting CD40 for activation of antigen presenting cells, in order to overcome tumor induced T cell tolerance, have shown promising results in cell and animal models. However, further trials have gained limited results due to severe side reactions.
View Article and Find Full Text PDFJ Vis Exp
September 2025
Department of Biochemistry & Molecular Biology, Dalhousie University; Department of Chemistry, Dalhousie University; School of Biomedical Engineering, Dalhousie University;
This corrects the article 10.3791/68714.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Key Lab of Guangdong Province for High Property and Functional Polymer Materials, School of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China. Electronic address:
Inspired by spider silk, polyphenolic nanodots (PTa) loaded multi-layer MXene (mMXene-PTa) through hydrogen and coordination bonds was prepared by self-polymerizing tannic acid on mMXene and used as a new crosslinker for polyvinyl alcohol (PVA). Together with starch (ST), mMXene-PTa was compounded with PVA and exfoliated to fabricate PVA/ST/mMXene-PTa nanocomposite. The phenolic hydroxyl groups in PTa formed high-density H-bonds with PVA and ST, creating an organic-inorganic dynamic crosslinking network with mMXene-PTa as nodes.
View Article and Find Full Text PDFLab Chip
September 2025
Institute for Life and Medical Sciences, Kyoto University, Japan.
Multiplexed fluid control is a demanding task in various studies in life sciences and bioengineering. Herein, we present open-source microfluidic sequence automation (MiSA) that offers flexible and multiplexed fluid control for various applications, providing constant flow pressure-based feedback control with 10-plex capability and pulsed flow on the order of 100 ms. MiSA was self-contained, including a pressure source, and employed an Arduino Micro to integrate ten solenoid valves, an off-the-shelf pressure regulator, and a flow sensor to balance cost and reliability.
View Article and Find Full Text PDF