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Introduction: Hydatid disease (HD) is a zoonotic infection caused by echinococcus granulosus tapeworms. HD accounts for approximately one million cases worldwide. HD is more prevalent in endemic areas, such as the Mediterranean region.
Presentation Of Case: A middle-aged male patient presented with right flank pain for years. His vital signs and physical examination were unremarkable. The whole-body bone scan revealed an area along the sixth rib's posterior arch with increased metabolic activity and CT and MRI were compatible with a hydatid cyst. The cyst was surgically resected and irrigation of the area with hypertonic saline was done. Medical treatment with albendazole was initiated and the patient had no complications.
Discussion: Bone involvement is an uncommon finding in HD and involvement of the ribs is even more scarce. Surgical resection complemented with medical treatment is the preferred approach.
Conclusion: In the Mediterranean and middle eastern regions, high infection rates with E. granulosis are evident hence, uncommon manifestations of the disease should be regarded. Although renal stones are far more prevalent when in endemic areas of HD, the physician should also consider skeletal HD as a differential diagnosis.
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http://dx.doi.org/10.1016/j.ijscr.2023.107888 | DOI Listing |
Acta Trop
September 2025
State Key Laboratory for Animal Disease Control and Prevention/College of Veterinary Medicine, Lanzhou University/ WOAH Reference Laboratory for Cysticercosis/ National Para-reference Laboratory for Animal Echinococcosis/Gansu Province Research Center for Basic Disciplines of Pathogen Biology/ Key L
Cystic echinococcosis (CE) and Taenia spp. infections are major zoonotic helminthiases with substantial public health and economic burdens, particularly in endemic regions. Despite their classification as neglected tropical diseases (NTDs), these tapeworm infections remain understudied in Nigeria.
View Article and Find Full Text PDFJ Immunoassay Immunochem
September 2025
Área Inmunología, Departamento de Biociencias (DEPBIO), Facultad de Química, Universidad de la República, Montevideo, Uruguay.
Immunoassays are complementary diagnostic tools in human cystic echinococcosis (CE) despite sensitivity/specificity limitations, and synthetic peptides have been suggested to potentially overcome disadvantages reported for traditional antigens. Herein, a systematic study comparing the immunodiagnostic performance of AgB1 versus synthetic peptides derived from its sequence was carried out. Thus, a eukaryotic-expressed recombinant AgB1 was assessed, together with a reported synthetic peptide (p176, N-terminal portion of AgB1) and two new peptides within p176 (namely pB1a and pB1b) corresponding to predicted linear B-cell epitopes.
View Article and Find Full Text PDFAsian Cardiovasc Thorac Ann
September 2025
Department of Radiology, Academic Hospital of Tangiers, Tangiers, Morocco.
Direct fistulization of a hepatic hydatid cyst into the lung, causing rapid pulmonary destruction, is exceedingly rare. We report a 41-year-old male presenting with acute asphyxia due to a complicated hepatic hydatid cyst with a giant transdiaphragmatic fistula into the right lung, leading to complete lung destruction and massive tracheobronchial aspiration. Emergency right pneumonectomy was performed for irreversible lung damage.
View Article and Find Full Text PDFFront Cell Infect Microbiol
September 2025
Department of Laboratory Medicine and Sichuan Provincial Key Laboratory for Human Disease Gene Study, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Objective: This hospital-based case-control study aims to evaluate hematological and biochemical markers for the diagnosis of cystic echinococcosis (CE) in the Tibetan population of Sichuan.
Methods: This study involved 83 patients diagnosed with CE and 45 healthy controls. Diagnosis of CE was confirmed through antibody and imaging tests, followed by an analysis of differences in blood and biochemical markers.
Front Immunol
September 2025
State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, Clinical Medicine Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Background: cyst fluid (EgCF) is a complex mixture of parasite's containing a variety of antigens. Th9 cells are a newly reported subpopulation of Th cells whose primary function is to secrete IL-9 and exert biological effects. Research on whether antigens in the vesicle fluid can evade the host immune response by increasing IL-9 secretion is limited.
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