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Electrospun polymer nanofibers (EPNF) constitute one of the most important nanomaterials with diverse applications. An overall review of EPNF is presented here, starting with an introduction to the most attractive features of these materials, which include the high aspect ratio and area to volume ratio as well as excellent processability through various production techniques. A review of these techniques is featured with a focus on electrospinning, which is the most widely used, with a detailed description and different types of the process. Polymers used in electrospinning are also reviewed with the solvent effect highlighted, followed by a discussion of the parameters of the electrospinning process. The mechanical properties of EPNF are discussed in detail with a focus on tests and techniques used for determining them, followed by a section for other properties including electrical, chemical, and optical properties. The final section is dedicated to the most important applications for EPNF, which constitute the driver for the relentless pursuit of their continuous development and improvement. These applications include biomedical application such as tissue engineering, wound healing and dressing, and drug delivery systems. In addition, sensors and biosensors applications, air filtration, defense applications, and energy devices are reviewed. A brief conclusion is presented at the end with the most important findings and directions for future research.
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http://dx.doi.org/10.3390/polym15010065 | DOI Listing |
Compr Rev Food Sci Food Saf
September 2025
Department of Seafood Processing Technology, Faculty of Fisheries, Cukurova University, Adana, Turkey.
Microbial spoilage and oxidation are significant causes of food deterioration, contributing to food waste of up to 30%. To mitigate these losses, active food packaging is an effective solution. Considering the excellent properties of nanofibers produced by electrospinning, integrating active food packaging functionality with nanofiber technology offers an ideal approach enhancing preservation.
View Article and Find Full Text PDFRSC Adv
August 2025
Department of Bioengineering and iBB - Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa Av. Rovisco Pais Lisboa 1049-001 Portugal
Bone-related injuries represent a major global challenge, particularly for the aging population. While bone has self-healing capabilities, large defects and non-union fractures often fail to completely regenerate, leading to long-term disability and the need for surgical intervention. Autologous bone grafts remain the gold standard for such procedures, but challenges such as limited donor availability and donor site comorbidity persist.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
September 2025
College of Food and Chemical Engineering, Shaoyang University, Shaoyang 422000, China. Electronic address:
Diclofenac sodium (DS), a non-steroidal anti-inflammatory drug used for treating inflammatory pain, has a short elimination half-life, which can lead to fluctuations in blood drug concentration. Therefore, developing sustained-release formulations is necessary to meet clinical needs. Biodegradable polymers exhibit excellent sustained-release properties and good biocompatibility, making them suitable for processing into nanofiber-based drug delivery systems via electrospinning technology.
View Article and Find Full Text PDFPharm Dev Technol
September 2025
Department of Pharmaceutics, Faculty of Pharmacy, Damanhur University, Damanhur, Egypt.
The dual solubility enhancement effect of nanofiber technology and pH-sensitive Eudragit L100-55 and S100 on class IV Cefditoren pivoxil (CEF) was studied. Nanofibers of different drug-polymer ratios were prepared. In-vitro characterization of CEF-loaded nanofibrous systems was performed through scanning electron microscopy (SEM), differential scanning calorimetry (DSC), and in-vitro drug release.
View Article and Find Full Text PDFJ Food Sci
September 2025
College of Light Industry and Food Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
To address post-harvest issues of litchi, including browning, water loss, and nutrient degradation, a moisture microenvironment-regulating electro spun membrane was prepared by incorporating hydrophobic carnauba wax (CW)@nano silica (SiO) composite powder into a polyethylene terephthalate (PET) matrix via electro spinning. The dynamic water penetration equilibrium was evaluated by monitoring the water vapor absorption of the electrospun membrane within 12 h, while the effects of CW@SiO on the micro-structure, mechanical properties, hydrophobicity, and thermal stability were investigated. Results showed that the tensile strength of the PET-2.
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