Isomer-specific perfluoroalkyl acids accumulation, excretion and maternal transfer to eggs in chickens around a fluorochemical manufactory in China.

The co-existing of multiple Per- and polyfluoroalkyl substances (PFASs) might pose more complicated situation for the exposure risk of environment and biota, especially for the surrounding area of the contaminated communities. In this study, tissues and organs of free-ranged chickens, paired eggs, corresponding feces, water, soil/dust, and feed samples around a fluorochemical manufactory were collected to investigate the tissue-isomer-specific accumulation, elimination and maternal transfer to eggs of PFASs. Free-ranged chickens had much higher ∑PFASs concentrations than farm chickens, and PFBA and PFOS were the predominant PFASs in tissues and organs, which is consistence with the electrochemical fluorination (ECF) production pattern of this manufactory. This result implied that PFASs released from manufactory production is a direct exposure source to the chickens. ∑PFASs concentrations in yolk samples were higher than other tissues and organs, while the concentrations in albumen were lowest. Isomer profiles analysis indicated that n-PFOS proportions in tissues, organs, yolk, and albumen ranged from 85.3 %-98.1 %, whereas in the feces with the percentage of 72.9 %, indicating that the branched PFOS isomers showed faster excretion rate than n-PFOS for chickens. Resident's estimated daily intakes (EDIs) of ∑PFASs via chicken were in the range of 6.41 to 107.18 ng/kg·bw/d. Notably, the EDIs of the sum of four PFASs were higher than the TDI of EFSA in 2020, indicating potential health risks.