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is a parasitic weed species that inflicts worldwide noxious effects in many broadleaf crops due to its capacity to withdraw nutrients and water directly from the crop vascular system using haustorial connections. control in the majority of crops affected is non-existent, and thus, research for the development of control methods is needed. Hydrocinnamic acid occurs naturally in the rhizosphere, playing regulatory roles in plant-plant and plant-microbe communities. The toxicity of hydrocinnamic acid against was recently identified. In the present work, a structure-activity relationship study of 21 hydrocinnamic acid analogues was performed to identify key structural features needed for its allelopathic action against the seedling growth of this parasitic plant. The findings of this study provide the first step for the design of herbicides with enhanced activity for the control of infection.
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http://dx.doi.org/10.3390/plants11212846 | DOI Listing |
Int J Food Microbiol
September 2025
College of Food Science, Southwest University, Chongqing 400715, PR China; Research Center for Fruits and Vegetables Logistics Preservation and Nutritional Quality Control, Southwest University, PR China; Chongqing Key Laboratory of Speciality Food Co-Built by Sichuan and Chongqing, Chongqing 400715
Postharvest softening of Agaricus bisporus (A. bisporus) is a major factor in its quality deterioration. However, the physiological changes involved in softening of A.
View Article and Find Full Text PDFPlant Physiol Biochem
August 2025
Department of Biology, University of North Florida, Jacksonville, FL, United States. Electronic address:
Infection of the marine subtropical seagrass Thalassia testudinum Banks ex König by pathogenic Labyrinthula sp. was found to induce lesion progression, alterations to the host's oxidative metabolism, and production of defense metabolites over the early stages of infection (monitored over a 72-hr time course). By 48-hr post-infection, host oxygen consumption, internal reactive oxygen concentrations, and caspase-3 proteolytic activity reached their highest levels.
View Article and Find Full Text PDFSynth Syst Biotechnol
September 2025
Department of Biology, National Pathogen Collection Center for Aquatic Animals, Shanghai Ocean University, Shanghai, 201306, China.
A family of inwardly-rectifying potassium (Kir) channels plays a key role in the regulation of cellular potassium (K) balance, affecting muscle, nerve and immune function. Kir channels are comprised of either homologous or heterologous tetramer of Kir subunits, each of which contains two-transmembrane domains. The challenges associated with the precise biophysical characterization of Kir channels have limited our understanding of this important class of molecules.
View Article and Find Full Text PDFbioRxiv
May 2025
Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute of the Cleveland Clinic; Cleveland, OH, USA.
Obesity-associated metabolic disorders such as type 2 diabetes mellitus and metabolic dysfunction associated fatty liver disease are major global health concerns, yet current pharmacological treatments often present with major side-effects. Dietary interventions including polyphenol-rich foods offer a promising complementary option for obesity amelioration, but their efficacy is dependent on specific gut microbial metabolism and the underlying molecular mechanisms mostly remain elusive. Here, we demonstrated that dietary elderberry (Eld) extract abrogates the effects of an obesogenic diet in a gut microbiota-dependent manner, by preventing insulin resistance and reducing hepatic steatosis in mice.
View Article and Find Full Text PDFSci Rep
May 2025
Institute of Psychology, University of Education, Ludwigsburg, Germany.
The gut microbiome significantly influences physical and mental health, including the synthesis and metabolism of hormones and the detoxification of heavy metals, which are linked to behavioural disorders. This study investigated the associations of these biological factors with the behaviour of primary school children, specifically examining the effects of heavy metals, catecholamines, and microbiome-associated metabolites of dopamine, noradrenaline, adrenaline, and thyroxine precursors. Urine samples from 87 unselected primary school children were analysed to assess heavy metal load (arsenic, cadmium, lead, mercury), noradrenaline/adrenaline ratio, and microbiome-associated metabolites of phenylalanine, tyrosine and L-dopa (3-phenylpropionic acid, p-OH-phenylacetic acid, 4-hydroxybenzoic acid, 3,4-dihydroxyphenylpropionic acid).
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