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Cases: We present 2 cases (19- and 40-year-old women) of lumbosacral spinal deformity with sacroiliac joint destruction. Reconstruction surgery using a fibular strut autograft was performed in both patients, and spinal reconstruction and fusion were successfully maintained without bone resorption for at least 7 years.
Conclusion: This is the first report of reconstructive surgery using a fibular strut bone graft for lumbosacral deformity with destruction of the sacroiliac joint in patients with neurofibromatosis type 1 (NF-1). These findings suggest that reconstruction with a fibular strut autograft is useful for lumbosacral spinal deformity that includes destruction of the sacroiliac joints in NF-1.
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http://dx.doi.org/10.2106/JBJS.CC.21.00653 | DOI Listing |
Ann Neurol
September 2025
Spinal Cord Injury Center, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Objective: Impaired ability to induce stepping after incomplete spinal cord injury (SCI) can limit the efficacy of locomotor training, often leaving patients wheelchair-bound. The cuneiform nucleus (CNF), a key mesencephalic locomotor control center, modulates the activity of spinal locomotor centers via the reticulospinal tract. Even with severe corticospinal damage, the widely distributed reticulospinal fibers frequently cross the lesion, and lumbosacral spinal locomotor centers remain responsive.
View Article and Find Full Text PDFProc Inst Mech Eng H
September 2025
IDMEC, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.
Low back pain is estimated to affect more than 70% of the population. Recently, interspinous posterior devices are gaining attention as a less invasive alternative to the traditional pedicle screw systems. However, since most of these devices are not suitable for the L5-S1 segment, the goals for this study are to design a tailored fixation system for the L5-S1 level and to study its effects on the degenerated spine.
View Article and Find Full Text PDFPurpose: This study examines the association between neurogenic injury and lumbar intervertebral disc degeneration (LDD) in tethered cord syndrome (TCS) by comparing lumbar sagittal parameters and disc degeneration between patients with normal and abnormal somatosensory evoked potential (SSEP) findings.
Methods: We retrospectively analyzed clinical data from 43 patients diagnosed with TCS between July 2018 and July 2024. Based on tibial nerve somatosensory evoked potential (SSEP) examination results, patients were categorized into SSEP-normal and SSEP-abnormal groups.
Cureus
August 2025
Anatomy, Arizona College of Osteopathic Medicine (AZCOM) Midwestern University, Glendale, USA.
This case study focuses on the atypical nerve contributions and branching patterns of the lumbar plexus in two human body donors at Midwestern University. It discusses their implications for pathology and surgical outcomes. Variations were identified in the anterior rami contributions and branching patterns of the lumbar plexus in both donors, predominantly in the lateral femoral cutaneous nerve (LFCN).
View Article and Find Full Text PDFBioelectron Med
September 2025
International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, Canada.
Unlabelled: Cervical spinal cord injury (SCI) impairs sensorimotor and autonomic functions. We investigated the effects of lumbosacral transcutaneous spinal cord stimulation (tSCS) on urinary bladder, bowel, and sexual function as well as cardiovascular and sensorimotor functions in one individual with chronic clinically motor-complete cervical SCI, 11 years post-injury. Following 30 sessions of lumbosacral tSCS, the individual presented with improved urinary bladder compliance as well as anorectal function in parallel with mitigation of the severity of autonomic dysreflexia during filling cystometry and anorectal manometry.
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