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Solitary fibrous tumor/hemangiopericytoma (SFT/HPC) is a rare intracranial tumor that arises from pericytes surrounding the blood vessels. Solitary fibrous tumor/hemangiopericytoma accounts for less than 1% of primary brain tumors and is classified as grades I, II, or III based on mitotic count. These tumors often masquerade as meningiomas. Histologically, SFT/HPC is vascular with high cellularity and often surrounded by connective tissue. Immunohistochemistry is positive for stat 6, vimentin, and CD34. Although aggressive surgical resection is the mainstay of treatment, close long-term follow-up is necessary as recurrence or extra cranial metastasis can present several years after resection.
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http://dx.doi.org/10.1177/23247096221132244 | DOI Listing |
J UOEH
August 2025
Department of Radiology, University of Occupational and Environmental Health, Japan.
Synovial chondromatosis (SC) is a locally aggressive neoplasm consisting of multiple hyaline cartilaginous nodules. This neoplasm typically manifests as multiple intra-articular calcified or uncalcified nodules, whereas the extraarticular form is particularly rare. We herein present a case of solitary extraarticular SC arising in the hand and correlate the imaging findings with pathologic findings.
View Article and Find Full Text PDFJ Med Case Rep
August 2025
Department of Oncology, Guangdong Provincial Corps Hospital of the Chinese People's Armed Police Forces, Guangzhou, China.
Background: Solitary fibrous tumors are rare central nervous system neoplasms with high rates of local recurrence and distant metastasis. To date, no instances of metastatic dissemination from the spine to the ventricle with malignant progression have been documented.
Case Presentation: A 32-year-old male patient of Chinese ethnicity was diagnosed with a grade 2 intraspinal solitary fibrous tumor, demonstrating metastatic spread to the trigone region of the lateral ventricle.
J Neurosurg
August 2025
1Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai.
Objective: Intracranial solitary fibrous tumor (ISFT) is a rare type of neoplasm that resembles meningioma. The authors aimed to compare the long-term postoperative outcomes between patients with ISFT and those with meningioma, and to create a model to identify patients with ISFT who are at high risk of recurrence.
Methods: A total of 187 patients with de novo ISFT and 473 patients with de novo meningioma who underwent tumor resection at a single neurosurgical center from 2013 to 2021 were included in this study.
Diagn Cytopathol
August 2025
Department of Pathology and Division of Pathology, Osaka Medical and Pharmaceutical University, Osaka, Japan.
Solitary fibrous tumors (SFTs) are rare neoplasms characterized by spindle neoplastic cell proliferation within collagenous stroma and prominent dilated vasculature. They present a wide histopathological spectrum, ranging from hypocellular lesions with a rich collagenous stroma to hypercellular lesions with scant stroma. Meningeal SFTs are usually hypercellular, and their cytological features remain poorly characterized.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
Faculty of Medicine, University of Aleppo, Aleppo, Syria. Electronic address:
Introduction And Importance: Endobronchial solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that account for less than 2 % of all SFTs. Diagnosis and treatment are major challenges because of their rarity and varied presentation. We present a case of endobronchial SFT that was successfully treated with minimally invasive bronchoscopic excision and review the literature to highlight the latest developments in diagnosis and treatment.
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