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Loneliness is emerging as a public health problem. Due to the social and emotional attributes of loneliness, there is a lack of multidimensional-related research and an effective scale with which to evaluate the loneliness of older adults in China. We intend to translate and psychometrically validate the Chinese version of the loneliness scale for older adults (C-LSOA). A cross-sectional study was conducted with a sample of 415 older adults in Huzhou, China. Content validity, construct validity, concurrent validity, and reliability were used to assess the scale's psychometric properties. Exploratory factor analysis of the C-LSOA extracted five common factors, and confirmatory factor analysis fit well. The model fit parameter values were X/df = 2.060, CFI = 0.912, TLI = 0.902, RMSEA = 0.064, and SRMR = 0.060. The scale's content validity index was 0.93. The Cronbach's α for the total scale was 0.868, and the test-retest result was 0.854. The correlation between the C-LSOA and UCLA was 0.886, with good concurrent validity. The results indicated that the C-LSOA could be used to measure the loneliness of older adults in Chinese communities.
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http://dx.doi.org/10.1016/j.gerinurse.2022.10.004 | DOI Listing |
JAMA Dermatol
September 2025
Department of Population Health, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
Importance: Increasingly, strategies to systematically detect melanomas invoke targeted approaches, whereby those at highest risk are prioritized for skin screening. Many tools exist to predict future melanoma risk, but most have limited accuracy and are potentially biased.
Objectives: To develop an improved melanoma risk prediction tool for invasive melanoma.
JAMA Netw Open
September 2025
Oncostat U1018, Institut National de la Santé et de la Recherche Médicale (INSERM), Ligue Contre le Cancer, Paris-Saclay University, Villejuif, France.
Importance: Antibiotics, steroids, and proton pump inhibitors (PPIs) are suspected to decrease the efficacy of immunotherapy.
Objective: To explore the association of comedications with overall survival (OS) in patients with advanced non-small-cell lung cancer (NSCLC).
Design, Setting, And Participants: This nationwide retrospective cohort study used target trial emulations of patients newly diagnosed with NSCLC from January 2015 to December 2022, identified from the French national health care database.
JAMA Netw Open
September 2025
School of Nursing, Capital Medical University, Beijing, China.
Importance: The efficacy of home end-of-life care in enhancing the quality of life for terminally ill patients and families has been well documented. While previous studies have explored perspectives on quality home palliative care and end-of-life care in several countries, limited knowledge exists regarding its specific components in the Chinese context.
Objective: To explore the core elements that constitute quality home end-of-life care in China.
JAMA Netw Open
September 2025
Harvard Medical School, Boston, Massachusetts.
Importance: Research in behavioral economics has demonstrated that people have irrational biases, which make them susceptible to decisional shortcuts, or heuristics. The extent to which physicians consciously might use nudges to exploit these heuristics and thereby influence their patients' decision-making is unclear. In addition, ethical questions about the conscious use of nudges in medicine persist, yet little is known about how physicians experience and perceive their use.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla.
Importance: Janus kinase (JAK) inhibitors are highly effective medications for several immune-mediated inflammatory diseases (IMIDs). However, safety concerns have led to regulatory restrictions.
Objective: To compare the risk of adverse events with JAK inhibitors vs tumor necrosis factor (TNF) antagonists in patients with IMIDs in head-to-head comparative effectiveness studies.