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A 50-year-old man was referred to our hospital with myelitis associated with a 10-months history of progressive muscle weakness in the left leg. Neurological examinations demonstrated diffuse muscle weakness of the left leg, touch hypoesthesia of the right leg, reduced pain sensation below the right nipple, left pyramidal sign, and urinary incontinence. On the basis of thoracic spinal MRI and thoracic CT myelography, revealing anterior displacement of the spinal cord and enlargement of the posterior subarachnoid space at the Th4 vertebral level, we diagnosed the patient as having idiopathic spinal cord herniation with incomplete Brown-Séquard syndrome. After microsurgical release of the spinal cord and subsequent covering of the anterior dural defect with an artificial dura mater, the symptoms improved without progression. Clinicians should consider spinal cord herniation as a cause of slowly progressive thoracic myelopathy with Brown-Séquard syndrome.
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http://dx.doi.org/10.5692/clinicalneurol.cn-001767 | DOI Listing |
J Back Musculoskelet Rehabil
September 2025
Neurology, Akdeniz University, Antalya, Turkey.
BackgroundSpinal cord injury is a complex condition affecting millions globally, often requiring extensive rehabilitation. YouTube is increasingly utilized by spinal cord injury-patients and caregivers for rehabilitation information, despite potential misinformation risks. However, few studies have assessed the quality of spinal cord injury -related content on this platform.
View Article and Find Full Text PDFTissue Eng Regen Med
September 2025
Department of Biomedical Science, Catholic Kwandong University, 24 Beomil-ro 579beon-gil, Gangneung-si, Gangwon-do, South Korea.
Background: Neurotraumatic conditions, such as spinal cord injury, brain injury, and neurodegenerative conditions, such as amyotrophic lateral sclerosis, pose a challenge to the field of rehabilitation for its complexity and nuances in management. For decades, the use of cell therapy in treatment of neurorehabilitation conditions have been explored to complement the current, mainstay treatment options; however, a consensus for standardization of the cell therapy and its efficacy has not been reached in the medical community. This study aims to provide a comparative review on the very topic of cell therapy use in neurorehabilitation conditions in an attempt to bridge the gap in knowledge.
View Article and Find Full Text PDFNeurosurg Rev
September 2025
Department of Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, Tübingen, Germany.
Purpose: To share our clinical experience with conservative management of isolated spinal arterial aneurysms (ISAs) and to identify clinical scenarios where conservative management may be appropriate, in the context of a literature review.
Methods: We performed a retrospective review of spinal angiograms from two German neuroradiology centers and conducted a systematic literature review of reported ISA cases. We analyzed demographics, clinical presentation, imaging findings, treatments, and outcomes.
Comput Methods Biomech Biomed Engin
September 2025
Robotics Institute, Ningbo University of Technology, Ningbo, China.
Surface electromyography (sEMG) holds great potential in walking function evaluation. Compressed sensing (CS) leverages the sparsity of signals to decrease the number of samples required. In this study, a sEMG CS algorithm for spinal cord injury (SCI) patients based on regularized orthogonal matching pursuit (ROMP) was introduced.
View Article and Find Full Text PDFEur J Neurosci
September 2025
Department of Anesthesiology and Pain Medicine, University of California Davis, Davis, California, USA.
Voltage-gated K channels of the Kv2 family coassemble with electrically silent KvS subunits in specific subpopulations of brain neurons, forming heteromeric Kv2/KvS channels with distinct functional properties. Little is known about the composition and function of Kv2 channels in spinal cord neurons, however. Here, we show that while Kv2.
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