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Objectives: Globally, the burden of disease caused by alcohol use has been steadily increasing, including in Thailand. In this study, we aim to test the effectiveness of Anderson et al.'s suggested three approaches to change the collective social norms, which comprise of: (1) providing information and an understanding about alcohol use behaviour, its causes and distribution; (2) focusing strategies on groups rather than individuals; and (3) strengthening supportive laws, regulations and approaches.
Study Design: We employed a mixed-methods approach. Evidence was gathered from literature review and in-depth interviews with key individuals who are responsible for community-based interventions to alcohol marketing strategies in Thailand.
Methods: We chose to focus on two case studies in Nan and Surin provinces, where hospital-based longitudinal data (8 years) were available. Changes in casualties related to the harmful use of alcohol, resulting from interactions between community-based interventions and alcohol marketing during the time of annual festivals were investigated. We employed the theory of change (ToC) defined by Vogel to guide the data collection and analysis. We reviewed literature from online databases and grey literature to generate causal-loop diagrams.
Results: We created a causal-loop diagram to describe the complexity of harmful alcohol use, its related factors, context, interventions and outcomes. Over the decade between 2006 and 2015, community-based strategies led to a substantial reduction of casualties (initially a 50% reduction, rising to an 80-90% reduction by the end of the study period) during the time of the festivals.
Conclusions: The reduction in injuries and fatalities could be a result of the concerted actions, including legal sanctions of alcohol beverage sales and advertisement, and public education to raise awareness and impart knowledge of the harmful use of alcohol. The actions were organised by a coalition of civil society, health professionals, public authorities and community leaders using hospital-based data on the adverse effects of harmful alcohol use to mobilise political support at the provincial level. The availability of long-term financial support as a catalytic source of funds and the presence of a comprehensive alcohol control act enabled framing and mobilisation of local resources and political support.
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http://dx.doi.org/10.1016/j.puhip.2021.100116 | DOI Listing |
ACS Catal
August 2025
Department of Chemistry, University of Southern California, Los Angeles, California 90089, United States.
Chlorinated hydrocarbons are widely used as solvents and synthetic intermediates, but their chemical persistence can cause hazardous environmental accumulation. Haloalkane dehalogenase from (DhlA) is a bacterial enzyme that naturally converts toxic chloroalkanes into less harmful alcohols. Using a multiscale approach based on the empirical valence bond method, we investigate the catalytic mechanism of 1,2-dichloroethane dehalogenation within DhlA and its mutants.
View Article and Find Full Text PDFCochrane Database Syst Rev
September 2025
Department of Family Medicine, University of Alberta, Edmonton, Alberta, Canada.
Background: Opioid use disorder (OUD) is commonly treated in specialized care settings with long-acting opioid agonists, also known as opioid agonist therapy, or OAT. Despite the rise in opioid use globally and evidence for a 50% reduction in mortality when OAT is employed, the proportion of people with OUD receiving OAT remains small. One initiative to improve the access and uptake of OAT could be to offer OAT in a primary care setting; primary care clinics are more numerous, might reduce the visibility and potential stigma of receiving treatment for OUD, and may facilitate the care of other medical conditions that are unrelated to OUD.
View Article and Find Full Text PDFACS Omega
September 2025
Department of Health Sciences, College of Natural Sciences, Can Tho University, Can Tho 94000, Vietnam.
Anthocyanins, natural antioxidants found in L. flowers, exhibit instability when exposed to high temperatures. Therefore, to heat-protect the anthocyanins, this investigation produced extract-loaded polymeric (polyethylenimine (PEI) or poly-(vinyl alcohol) (PVA)) functionalized silk fibroin nanoparticles using a green/sustainable process.
View Article and Find Full Text PDFIndian J Psychiatry
August 2025
Department of Community Medicine, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Background: Illicit substance use is a major social issue affecting youth worldwide. Early identification of its drivers is essential to implement effective interventions and protect youth from its harmful consequences.
Aim: To examine patterns and risk factors of illicit substance use among young adults and explore perceptions of students and teachers on the issue.
Drug Alcohol Depend Rep
September 2025
University of Illinois Chicago, Department of Psychology, United States.
Background: Cannabis use in pregnancy is increasing, despite evidence linking perinatal cannabis use (PCU) to maternal and infant health risks. To investigate factors contributing to increasing PCU, this study used qualitative interviews to examine beliefs and perceptions of PCU.
Methods: Semi-structured qualitative interviews with pre- and post-pregnancy women examined beliefs and perceived benefits and harms of PCU.