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http://dx.doi.org/10.1186/s12935-022-02667-y | DOI Listing |
J Photochem Photobiol B
October 2025
College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China; Heilongjiang Provincial Key Laboratory of Ecological Utilizati
Oxidative stress from excessive accumulation of ROS drives several diseases, highlighting the need for efficient antioxidants. The antioxidant activity of excited-state genistein (Gen) and its methylated derivatives (5-MG, 4'-MG, and 7-MG) is systematically explored using density functional theory/time-dependent density functional theory (DFT/TD-DFT) calculations, molecular docking, and molecular dynamics simulation. Except for 5-MG, the rest of the isoflavones have excited state intramolecular proton transfer (ESIPT) property confirmed by potential energy curves as an ultrafast process, which further determines the molecular forms, namely enol (S) and keto* (S) forms.
View Article and Find Full Text PDFJ Mater Chem B
February 2025
Research Group of Nutrition and Health, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, China.
Correction for 'Phosphatidylserine-functionalized liposomes-in-microgels for delivering genistein to effectively treat ulcerative colitis' by Huijia Yan , , 2023, , 10404-10417, https://doi.org/10.1039/D3TB00812F.
View Article and Find Full Text PDFMolecules
December 2024
State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen Research Institute of the Hong Kong Polytechnic University, Shenzhen 518057, China.
In the original publication [...
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Laboratory of Translational Medicine and Nanotherapeutics, Department of Human Genetics and Molecular Medicine, School of Health Sciences, Central University of Punjab, Bathinda, India.
[This corrects the article DOI: 10.3389/fendo.2024.
View Article and Find Full Text PDFJ Am Heart Assoc
July 2024
Department of Nutrition, Center for Big Data and Population Health of IHM School of Public Health, Anhui Medical University Hefei Anhui China.
Background: The association between soy isoflavones intake and cardiometabolic health remains inconclusive. We investigated the associations of urinary biomarkers of isoflavones including daidzein, glycitein, genistein, equol (a gut microbial metabolite of daidzein), and equol-predicting microbial species with cardiometabolic risk markers.
Methods And Results: In a 1-year study of 305 Chinese community-dwelling adults aged ≥18 years, urinary isoflavones, fecal microbiota, blood pressure, blood glucose and lipids, and anthropometric data were measured twice, 1 year apart.