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Background: Individuals with lower limb amputation exhibit lower residual limb strength compared to their sound limb. Deficits in residual limb knee flexion and extension strength may impact functional performance during tasks relevant to daily living.
Research Question: Does knee flexor and extensor strength in the residual limb impact functional outcome measures, such as walking energetics and performance metrics, in individuals with unilateral transtibial amputation?
Methods: Fourteen individuals with traumatic unilateral transtibial amputation were recruited for this observational study. Participants completed metabolic testing at three standardized speeds based on leg length, as well maximum isokinetic knee flexion and extension strength for both residual and sound limbs. Participants also completed a series of functional outcome tests, including a two-minute walk test, timed stair ascent test, and four-square step test. Walking energetics (metabolic cost, heart rate, and rating of perceived exertion) and performance metrics were compared to percent deficit of residual limb to sound limb knee flexion and extension muscle strength. A linear regression assessed significant relationships (p < 0.05).
Results: A significant relationship was observed between percent deficit of knee extension strength and heart rate (p = 0.024) at a fast walking speed. Additionally, percent deficit knee flexion strength related to rating of perceived exertion at slow and moderate walking speeds (p = 0.038, p = 0.024). Percent deficit knee extension strength related to two-minute walk time performance (p = 0.035) and percent deficit knee flexion strength related to timed stair ascent time (p = 0.025).
Significance: These findings suggest the importance of strength retention of the residual limb knee flexion and extension musculature to improve certain functional outcomes in individuals with unilateral transtibial amputation.
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http://dx.doi.org/10.1016/j.gaitpost.2022.07.257 | DOI Listing |
Medicine (Baltimore)
September 2025
Department of Infectious Diseases, Third People's Hospital of Chengdu, Chengdu, China.
Rationale: Japanese spotted fever (JSF) is a rare tick-borne disease caused by Rickettsia japonica. Atypical manifestations and a lack of standardized diagnostic assays often result in delayed diagnosis and treatment, potentially leading to life-threatening complications.
Patient Concerns: A 57-year-old immunocompetent female from a region with no previously reported JSF cases presented with acute-onset high-grade fever (39.
J Arthroplasty
September 2025
Department of Orthopedic Surgery, Korea University College of Medicine, Ansan Hospital, Ansan-si, Gyeonggi-do, South Korea. Electronic address:
Background: Lower-limb alignment should be accurately assessed to achieve favorable outcomes after total knee arthroplasty (TKA). Compared to conventional alignment methods, the recently adopted hip-to-calcaneus (HTC) axis better reflects actual weight-bearing alignment by including hindfoot alignment. However, whether discrepancies between two mechanical alignments vary according to ankle osteoarthritis (OA) and whether such discrepancies are clinically meaningful remains unclear.
View Article and Find Full Text PDFCureus
August 2025
Diagnostic Radiology, Mardan Medical Complex, Mardan, PAK.
Introduction: Fractures are a common occurrence in childhood, with approximately one-third of boys and girls sustaining at least one fracture before the age of 17. Both-bone forearm fractures, particularly those involving the radius and ulna, are more common in the non-dominant hand and in boys and usually involve the distal portions of both bones. If not properly treated, these injuries can have a significant impact on limb function.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
September 2025
International School of Microelectronics, Dongguan University of Technology, Dongguan, China.
Many traditional classification networks directly use the limb two-lead signal (MLII) ECG signals as input for training. However, this method suffers from reduced accuracy when ECG features are not obvious, especially for premature heartbeats. To solve the issue, this paper proposed a novel network, namely CDLR-Net, that combines a Deep Residual Shrinkage Network (DRSN) with a Long Short-Term Memory (LSTM).
View Article and Find Full Text PDFProc Inst Mech Eng H
September 2025
Faculty of Medicine, Sirindhorn School of Prosthetics and Orthotics, Siriraj Hospital, Mahidol University, Bangkok, 10700 Thailand.
This study provides valuable guidance for simplifying fabrication procedures and enhancing the structural integrity and safety of carbon fiber (CF) laminate transfemoral (TF) prosthetic sockets. While the high specific strength of CF laminate sockets offers advantages over conventional plastics, essential production data-their orientation-dependent strength and optimal cure conditions-are lacking, often requiring complex, costly cure cycles. This study investigated (i) the influence of fiber orientation on TF prosthetic CF socket strength via finite element analysis (FEA) during standing, and (ii) optimal single-step Vacuum-Bag-Only (VBO) cure conditions for prepreg in a low-cost conventional oven.
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