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In view of the difficulty in obtaining the membrane bioreactor (MBR) membrane flux in real time, considering the disadvantage of the back propagation (BP) network in predicting MBR membrane flux, such as the local minimum value and poor generalization ability of the model, this article introduces tent chaotic mapping in the standard sparrow search algorithm (SSA), which improves the uniformity of population distribution and the searching ability of the algorithm (used to optimize the key parameters of the BP network). The tent sparrow search algorithm back propagation network (Tent-SSA-BP) membrane fouling prediction model is established to achieve accurate prediction of membrane flux; compared to the BP, genetic algorithm back propagation network (GA-BP), particle swarm optimization back propagation network (PSO-BP), sparrow search algorithm extreme learning machine(SSA-ELM), sparrow search algorithm back propagation network (SSA-BP), and Tent particle swarm optimization back propagation network (Tent-PSO-BP) models, it has unique advantages. Compared with the BP model before improvement, the improved soft sensing model reduces MAPE by 96.76%, RMSE by 99.78% and MAE by 95.61%. The prediction accuracy of the algorithm proposed in this article reaches 97.4%, which is much higher than the 48.52% of BP. It is also higher than other prediction models, and the prediction accuracy has been greatly improved, which has some engineering reference value.
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http://dx.doi.org/10.3390/membranes12070691 | DOI Listing |
Arch Cardiovasc Dis
September 2025
Department of Orthopaedics, Shaoxing Keqiao Women & Children's Hospital, Shaoxing 312030, Zhejiang, China. Electronic address:
Background: Sacubitril/valsartan is a widely used cardiovascular agent characterized by its dual inhibition of the renin-angiotensin-aldosterone system and neprilysin. However, existing evidence on the safety of sacubitril/valsartan is primarily limited to clinical studies; this results in an inability to provide a timely update on associated adverse events.
Aim: To mine and systematically describe adverse events related to sacubitril/valsartan from September 2015 to June 2024 using the Food and Drug Administration Adverse Event Reporting System (FAERS) database.
Sci Signal
September 2025
Department of Pathology, Microbiology and Immunology, New York Medical College, Valhalla, NY, USA.
Replication of HIV-1 requires the coordinated action of host and viral transcription factors, most critically the viral transactivator Tat and the host nuclear factor κB (NF-κB). This activity is disrupted in infected cells that are cultured with extracellular vesicles (EVs) present in human semen, suggesting that they contain factors that could inform the development of new therapeutics. Here, we explored the contents of semen-derived EVs (SEVs) from uninfected donors and individuals with HIV-1 and identified host proteins that interacted with HIV Tat and the NF-κB subunit p65.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
September 2025
Department of Pharmacy, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Maternity and Child Health Hospital, Fujian Medical University, #18 Daoshan Road, Fuzhou, Fujian, 350001, China.
Postpartum hemorrhage (PPH) is a life-threatening obstetric complication. We aimed to identify the drugs that associated with PPH based on the FDA Adverse Event Reporting System (FAERS) data, providing scientific evidence for targeted prevention of drug-related PPH risk factors. Data from 2004Q1 to 2025Q1 were extracted from FAERS, and disproportionality analysis was performed to identify potential drug signals.
View Article and Find Full Text PDFAndrology
September 2025
Department of Urology, The Second Affiliated Hospital of Shanxi Medical University, Taiyuan, China.
Background: Drug-induced hypogonadism is an underrecognized but significant adverse effect of various medications, contributing to male sexual dysfunction and infertility. Despite its clinical significance, comprehensive studies systematically identifying high-risk drugs remain limited.
Objectives: This study aimed to investigate the potential drugs associated with hypogonadism from FDA Adverse Event Reporting System.
Food Res Int
November 2025
Institute of Eco-Environmental Forensics, School of Environmental Science and Engineering, Shandong University, Qingdao 266237, China; Key Laboratory of Colloid and Interface Chemistry, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
The origin and grade of green tea significantly influence its market value, yet their concurrent authentication remains challenging. Here, we developed a robust method combining multiple metallic elements and back propagation neural network (BPNN) to identify the origin and grade of tea simultaneously. This strategy utilizes inductively coupled plasma atomic emission spectrometry (ICP-AES) to analyze the content of multiple elements in green tea (e.
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