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http://dx.doi.org/10.3389/fgene.2022.883199 | DOI Listing |
Vet Parasitol
August 2025
IHPE, Université de Montpellier, CNRS, Ifremer, Université de Perpignan Via Domitia, Perpignan, France.
Species of Lymnaeidae (Mollusca: Gastropoda) are important intermediate hosts of major parasites some of which are responsible for zoonosis worldwide. Particularly liver and rumen flukes impact livestock production with increasing costs due to flukicide treatments. In Europe, a single snail species, Galba trunctaula, is considered as responsible for the transmission of Fasciola hepatica and Calicophoron daubneyi, two trematode species with almost identical transmission cycles.
View Article and Find Full Text PDFJ Mol Cell Biol
August 2025
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730000, China.
African swine fever virus (ASFV) infection induces oxidative stress and produces oxidative DNA damage bases, including 8-oxoguanine (8-oxoG). It is essential to promptly repair these damages to maintain genome stability. The enzyme 8-oxoguanine DNA glycosylase 1 (OGG1) initiates the base excision repair (BER) pathway by recognizing and incising 8-oxoG and commonly regulates multiple biological processes by interacting with host and viral proteins.
View Article and Find Full Text PDFEMBO Mol Med
August 2025
School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Atherosclerosis is characterized by the accumulation of lipids and immune cells in the arterial wall, leading to the narrowing and stiffening of blood vessels. Innate and adaptive immunity are involved in the pathogenesis of human atherosclerosis. However, spatial organization and roles of immune cells during disease progression remain poorly understood.
View Article and Find Full Text PDFVirus Res
August 2025
Department of Clinical Laboratory, Eighth Affiliated Hospital of Guangxi Medical University, Guigang City People's Hospital, Guigang, Guangxi, China. Electronic address:
Background: Epstein-Barr virus-associated gastric carcinoma (EBVaGC) represents a distinct clinicopathological entity with unique molecular characteristics, including latent EBV infection and dysregulation of host tumor suppressors. However, the functional interplay between EBV circular RNAs (ebv-circRNAs) and p53 protein remains enigmatic. This study explored the role of ebv-circRPMS1, a previously uncharacterized ebv-circRNA, in EBVaGC pathogenesis.
View Article and Find Full Text PDFExp Eye Res
October 2025
State Key Laboratory Cultivation Base, Shandong Key Laboratory of Eye Diseases, Eye Institute of Shandong First Medical University, Qingdao, China; Eye Hospital of Shandong First Medical University, Jinan, China; School of Ophthalmology, Shandong First Medical University, Jinan, China. Electronic ad
Fungal keratitis (FK) is a serious corneal infection that can cause severe eye pain, corneal perforation, and potentially lead to permanent vision loss or blindness. The study aims to identify potential therapeutic targets in the pathogenesis of FK using an integrated omics approach. FK model was established in C57BL/6 mice by infecting their corneas with Fusarium solani.
View Article and Find Full Text PDF