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We performed a calendar-matched, 12-month, before (November 27, 2017 to November 26, 2018) and after (November 27, 2018 to November 26, 2019) study, to assess the utility of an emergency department-based HIV screening program. There were 710 and 14 335 patients screened for HIV during the pre and post-best practice alert (BPA) periods, respectively, representing more than a 20-fold increase in HIV screening following BPA implementation. Total HIV positive tests increased 5-fold following BPA implementation.
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http://dx.doi.org/10.1097/QAD.0000000000003282 | DOI Listing |
BMJ Open
September 2025
Public Health Ontario, Toronto, Ontario, Canada
Objectives: Canadian guidelines recommend HIV testing for individuals being evaluated for syphilis. Our objective was to examine three aspects of HIV testing (ie, if an HIV test occurred, the timing of the HIV test in relation to the syphilis test and the proportion with a positive HIV test result) among syphilis tests between 2017 and 2022 from individuals with no evidence of a previous HIV diagnosis.
Design And Setting: This study is a retrospective analysis of comprehensive laboratory testing data from Ontario's provincial public health laboratory.
Eur J Med Chem
September 2025
College of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, 201620, Shanghai, China; Shanghai Engineering Research Center of Pharmaceutical Intelligent Equipment, Shanghai University of Engineering Science, 201620, Shanghai, China. Electronic address:
The alkynyl group is vital in organic chemistry. It frequently occurs in natural compounds. Alkynyl -containing pharmaceuticals include contraceptive, anti-Parkinsonian, anti-HIV, and antifungal agents.
View Article and Find Full Text PDFInt J Epidemiol
August 2025
Department of Biostatistics and Informatics, University of Colorado, Aurora, CO, United States.
Background: Existing longitudinal cohort study data and associated biospecimen libraries provide abundant opportunities to efficiently examine new hypotheses through retrospective specimen testing. Outcome-dependent sampling (ODS) methods offer a powerful alternative to random sampling when testing all available specimens is not feasible or biospecimen preservation is desired. For repeated binary outcomes, a common ODS approach is to extend the case-control framework to the longitudinal setting.
View Article and Find Full Text PDFAm J Public Health
October 2025
Alexander Furuya, Asa Radix, Adam Whalen, Jessica Contreras, Jenesis Merriman, Krish J. Bhatt, Roberta Scheinmann, and Dustin T. Duncan are with the Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY. Yusuf Ransome is with the Department of Social and Behav
To examine how one's community connectedness may act as a source of resilience and promote HIV prevention and care behaviors among transgender women of color. We analyzed survey data from 313 transgender women of color living in New York City collected from August 2020 to November 2022. The Community Connectedness Scale asks participants about their baseline feelings of connection, feelings of inclusion, feelings of belonging, feelings of isolation, and feelings of being unlike in relation to the transgender community.
View Article and Find Full Text PDFPLoS One
September 2025
Chongqing Blood Center, Jiulongpo, Chongqing, China.
Background: In 2012, China raised the upper age restriction for blood donors from 55 to 60 years old. This study analyzed the impact of raising the upper age restriction on whole blood donor health, contribution to blood supply, and safety of blood.
Methods: The blood collection and donor hemovigilance data of the Chongqing Blood Center from 2012 to 2023 were analyzed to evaluate the safety of elderly blood donors.