Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Purpose: To compare the incidence of correction loss and survival rate between closed-wedge and open-wedge high tibial osteotomies (CWHTO and OWHTO, respectively) in patients with osteopenic and normal bone.
Methods: Retrospective review was conducted for 115 CWHTOs and 119 OWHTOs performed in osteopenic patients [- 2.5 < Bone mineral density (BMD) T scores ≤ - 1] and 136 CWHTOs and 138 OWHTOs performed in normal patients (BMD T score > - 1) from 2012 to 2019. Demographics were not different between CW- and OWHTOs in osteopenic and normal patients (n.s., respectively). Radiographically, the mechanical axis (MA), medial proximal tibial angle (MPTA), and posterior tibial slope (PTS) were evaluated pre- and postoperatively (2 weeks after HTO). The occurrence of hinge fractures was investigated using radiographs taken on the operation day. The correction change was calculated as the last follow-up value minus postoperative MPTA. Correction loss was defined when the correction change was ≥ 3°. The survival rate (failure: correction loss) was investigated.
Results: There were no significant differences in the pre and postoperative MA, MPTA, PTS, and value changes between CW- and OWHTOs in osteopenic and normal patients (n.s., respectively); the incidence of unstable hinge fractures also did not differ significantly (CWHTO vs. OWHTO = 7 vs. 7.6% in osteopenic patients; 2.9 vs. 3.6% in normal patients; n.s., respectively). The average correction change (CWHTO = - 0.6°, OWHTO = - 1.3°, p = 0.007), incidence of correction loss (CWHTO = 1.7%, OWHTO = 9.2%, p = 0.019), and 5-year survival rates (CWHTO = 98.3%, OWHTO = 90.8%, p = 0.013) differed significantly in osteopenic patients; there were no significant differences in these results in normal patients (n.s., respectively).
Conclusion: CWHTO was more advantageous than OWHTO regarding the correction loss in osteopenic patients. Intra- and postoperative care that consider poor bone quality will be required when performing OWHTOs in osteopenic patients.
Level Of Evidence: III.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00167-022-07006-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Osteocytic vinculin controls bone mass by modulating Mef2c-driven sclerostin expression in mice.
Bone Res
August 2025
Department of Biochemistry, Homeostatic Medicine Institute School of Medicine Shenzhen Key Laboratory of Cell Microenvironment, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Southern University of Science and Technology, Shenzhen, China.
The focal adhesion (FA) is the structural basis of the cell-extracellular matrix crosstalk and plays important roles in control of organ formation and function. Here we show that expression of FA protein vinculin is dramatically reduced in osteocytes in patients with aging-related osteoporosis. Vinculin loss severely impaired osteocyte adhesion and dendrite formation.
View Article and Find Full Text PDFEffects of Perioperative Proton Pump Inhibitor Use on Outcomes of Total Joint Arthroplasty Patients Who Have Osteoporosis and Osteopenia.
J Arthroplasty
August 2025
Luminis Health Orthopedics, Annapolis, Maryland.
Background: Proton pump inhibitors (PPIs) are commonly prescribed for gastrointestinal prophylaxis after total joint arthroplasty (TJA) during periods of increased nonsteroidal anti-inflammatory drug/aspirin use. However, studies have shown negative effects of PPIs on osseointegration, potentially leading to increased risk of implant-related complications, particularly among patients who have decreased bone density. The present investigation utilizes a large national database to compare outcomes between osteoporotic/osteopenic TJA patients who received routine prophylactic perioperative PPIs and those who did not.
View Article and Find Full Text PDFTeriparatide use is associated with increased odds of 2-year implant failure and revision in osteopenic patients undergoing cervical fusion.
J Craniovertebr Junction Spine
July 2025
Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, NY, USA.
Context: Cervical fusion outcomes are influenced by bone quality, with osteopenia increasing the risk of implant failure and revision surgery. The impact of teriparatide in this population remains unclear.
Aims: The aim of this study was to investigate the association between teriparatide use and 90-day medical complications, 2-year surgical complications, and hospital readmissions in this population.
Effect of hyperbaric oxygen therapy (HBO) on osteoblasts of elderly patients on calcification and osteoprotegerin.
J Orthop
September 2025
Bielefeld University, Medical School and University Medical Center OWL, Department of Orthopedics Klinikum Bielefeld-Mitte, Germany.
Background: Osteoporosis stands as one of the most prevalent bone diseases worldwide. This study aims to explore the effects of Hyperbaric Oxygen (HBO) therapy and substances that reduce reactive oxygen species (ROS), such as antioxidants, on osteogenic differentiation and key osteoporosis-related parameters in osteoblasts derived from elderly patients requiring hip arthroplasty.
Methods: An in vitro study was conducted using osteoblasts isolated from the femoral heads of 22 patients (78.
Hypophosphatasia: A case report.
World J Clin Cases
July 2025
Department of Research, American Society for Inclusion, Diversity, and Equity in Healthcare, Lewes, DE 19958, United States.
Background: Hypophosphatasia (HPP) is a rare metabolic disorder caused by low tissue-nonspecific alkaline phosphatase (ALP) activity, presenting symptoms from bone demineralization to tooth loss. It affects multiple systems and is diagnosed based on clinical symptoms, radiological findings, and lab tests. This case report emphasizes considering HPP in patients with unexplained bone pain and low ALP levels, especially with underlying osteopenia or osteoporosis.
View Article and Find Full Text PDF