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Epidermal microfluidic devices with long microchannels have been developed for continuous sweat analysis, which are crucial to assess personal hydration status and underlying health conditions. However, the flow resistance in long channels and the ionic concentration variation significantly affect the accuracy of both the sweat rate and electrolyte concentration measurements. Herein, we present a novel fluidic-controlled wearable platform for synchronously dropwise-detecting the sweat rate and total electrolyte concentration. The unconventional platform consisting of a vertically shortened channel, a pair of embedded electrodes and an absorption layer, is designed to minimize the flow resistance and transform sweat fluidics into uniform micro-droplets for chronological and dropwise detection. Real-time sweat conductance is decoupled from a square-wave-like curve, where the sweat rate and electrolyte concentration can be derived from the interval time and peak value, respectively. Flexible and wearable band devices are demonstrated to show their potential application for hydration status assessment during exercises.
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http://dx.doi.org/10.1016/j.bios.2022.114351 | DOI Listing |
Temperature (Austin)
June 2025
Department of Mechanical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Sweating is a vital thermoregulatory mechanism in humans for maintaining thermal balance during exercise and exposure to hot environments. The development of models that predict sweat rate based on body temperature has been ongoing for over half a century. Here, we compared predicted water loss rates (WLR) from these models to actual observations collected during 780 participant-exposures in three independent laboratory-based experiments.
View Article and Find Full Text PDFAdv Mater
September 2025
Guangxi Key Laboratory of Clean Pulp & Papermaking and Pollution Control, School of Light Industry and Food Engineering, Guangxi University, Nanning, 530004, China.
Triboelectric sweat sensors, endowed with the technical advantages of non-invasive ex vivo and in situ detection, have catalyzed the rapid advancement of personalized medicine and precision health management systems. However, the inherently low secretion rate and rapid evaporation of sweat pose significant challenges for its efficient collection and rapid analytical screening. This study leverages laser cutting and aqueous interfacial self-assembly strategies to develop a biomimetic heterogeneous wettability triboelectric material (HWTM).
View Article and Find Full Text PDFAm J Physiol Heart Circ Physiol
September 2025
Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, Medical School, University of Minnesota.
Objectives: While evidence suggests an association between vasomotor symptoms (VMS; hot flushes and night sweats) and elevated blood pressure (BP), it remains unknown whether females who experience VMS have elevated muscle sympathetic nerve activity (MSNA), a major modulator of BP. We hypothesized that postmenopausal females with VMS would have elevated BP and MSNA at rest and during stress compared to age-matched females without VMS.
Methods: Participants were grouped based on whether they currently or previously experienced VMS (n=43) or never experienced VMS (non-VMS; n=26).
Biosens Bioelectron
December 2025
Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea; PHI BIOMED Co., 168, Yeoksam-ro, Gangnam-gu, Seoul 06248, South Korea. Electronic address:
Noninvasive continuous glucose monitoring (CGM) offers a promising alternative to conventional blood-based approaches for diabetes management. Among various body fluids, sweat is an attractive medium to reflect the blood glucose levels in the body. However, technical challenges for the sweat analysis persist due to the low analyte concentrations, potential contamination, and inefficient sampling.
View Article and Find Full Text PDFRev Inst Med Trop Sao Paulo
August 2025
Universidade Federal do Maranhão, Hospital Universitário, São Luís, Maranhão, Brazil.
Chikungunya virus (CHIKV) is globally distributed and transmitted by Aedes mosquitoes, with a mortality rate of 0.8/1,000 cases. The heart is the second most affected organ, with the osteoarticular system being the first.
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