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Background: Evidence for the benefit of applying Fluoride Varnish FV to permanent teeth is generally very positive. However, the caries-inhibiting effect of FVs on primary teeth is still debatable.
Aim: To assess the effectiveness of fluoride varnish in prevention of early childhood caries in children over the period of 3 years in high fluoride areas.
Study Design: A double-blind cluster-randomized controlled trial was undertaken amongst 3-4 years old children. The varnish application was done at three points in the intervention group.
Results: Experimental group showed significantly lesser increment in mean ICDAS score than control group at both 12 month and 36 months. Preventive fraction was 72.4% at 12 months and 18.2% at 36 months. Multiple linear regression showed that at 12 months, intervention was the significant predictor with varnish group having 0.140 (95% CI 0.175-0.230) lower net caries increment. At 36 months, baseline ICDAS score and intervention were the significant predictors.
Conclusion: This study suggests that fluoride varnish is an effective and a safe mode of prevention of early childhood caries in children residing in high fluoride zone. However, the overall effect is influenced by the baseline caries status.
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http://dx.doi.org/10.17796/1053-4625-46.2.6 | DOI Listing |
PLoS One
September 2025
Australian Research Centre for Population Oral Health (ARCPOH), Adelaide Dental School, University of Adelaide, Adelaide, Australia.
Objective: Dental caries is one of the most common preventable diseases among Indigenous children. The study aimed to estimate the efficacy of an Early Childhood Caries (ECC) intervention among Aboriginal Australian children over 9 years, and to explore potential risk factors associated with dental caries among Indigenous Australian children.
Methods: Data were from a randomized controlled trial conducted in South Australia, Australia.
Int J Paediatr Dent
September 2025
Department of Pediatric Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Background: The amount of fluoride maintained in the oral cavity aids in the remineralization process.
Hypothesis/aim: To evaluate and compare plaque and salivary fluoride levels following applications of silver diamine fluoride (SDF), sodium fluoride varnish (NaFV), or both.
Design: Sixty preschoolers randomly received 38% SDF, 5% NaFV, or both (SDF + NaFV).
J Dent (Shiraz)
September 2025
Dept. of Pediatric Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Second Affiliation University of Applied Science and Technology, EbneSina Center, Tehran, Iran.
Background: Remineralizing early enamel lesions in primary dentition remain a significant challenge in dentistry, requiring innovative approaches to enhance enamel repair.
Purpose: This study aimed to evaluate the efficacy of a commercially available nanohydroxyapatite paste (Nano P), alone and in combination with air dielectric barrier discharge cold atmospheric plasma (CAP) and a 940-nm diode laser, on enamel remineralization.
Materials And Method: In this study, 105 intact anterior primary teeth were randomly assigned into one control and six experimental groups: (I) control, (II) Fluoride varnish, (III) Nano P, (IV) Nano P + dye + laser, (V) Nano P + laser, (VI) CAP, and (VII) Nano P + CAP.
Introduction: The WHO's Global Oral Health Action Plan towards 2030 suggests prioritizing cost-effective preventive and minimally invasive (MI) dental caries interventions as essential oral health care services. Given the high prevalence of dental caries among children, raising awareness of the limitations and research gaps of the existing economic evaluations assessing preventive and MI procedures is crucial.
Objective: This scoping review aimed to identify and map the relevant literature on economic evaluations for preventive and MI dental caries procedures among children under 12 years of age.
Glob Implement Res Appl
April 2025
Department of Industrial and Systems Engineering, Kennesaw State University, 1100 S. Marietta Pkwy, Marietta, GA 30060 USA.
Unlabelled: Early childhood caries affects many children, posing risks to dental and overall health. Fluoride varnish application during pediatric well-child visits has demonstrated efficacy in mitigating decay, yet rates remain notably low among medical providers. This study delves into the details of fluoride varnish adoption and delivery in pediatric practices and identifies associated barriers and facilitators by employing the updated Consolidated Framework for Implementation Research.
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