Microbial adherence and surface roughness of denture base materials: An study.

Implant-supported overdentures have become a widely accepted treatment modality for edentulous patients, offering enhanced retention, stability and comfort compared to conventional complete dentures. Hence, a total of 78 standardized specimens were fabricated and divided into three groups (n = 26 each): Group A (heat-cured PMMA), Group B (CAD/CAM milled resin) and Group C (3D-printed resin). Group B exhibited the lowest surface roughness (0.

Versatility of Temporalis Myofascial Flap in Maxillofacial Reconstruction: A Retrospective Study.

Aim: To evince the versatility of temporalis myofascial flap by assessing its success in patients of primary and secondary maxillofacial defects retrospectively.

Methodology: A retrospective study was designed to evaluate the patients of maxillofacial abnormalities repaired using temporalis myofascial flaps during the period of 2008 and 2017. Data regarding demographics, diagnosis of the disease made, site of disease involved, treatment done, outcome and short-term complication were extracted from the past patient records.

Investigating the association between tobacco use and oral health among security guards at a tertiary healthcare centre in New Delhi: a cross-sectional study.

Background: Tobacco usage is a major global public health concern, contributing to millions of deaths annually. This study focuses on security guards, an occupational group facing unique challenges, to investigate tobacco prevalence, usage patterns, and associated oral health risks.

Methods: A cross-sectional study was conducted among security guards at a Tertiary Health Care Centre, from October 2022 to February 2023.

Comparing the effectiveness of two educational methods for oral health management in COVID-19 pandemic among dental professionals.

The aim of this study was to train dentists on the different oral hygiene measures to be followed by COVID-19 patients via Webinar and Information Education Communication (IEC) Materials and compare the effectiveness of both. A total of 100 dental professionals were included by non-probability convenience sampling. Webinar and IEC Materials on oral hygiene measures, oral symptoms, and management strategies during COVID-19 were created and training was conducted for all dental professionals who registered themselves.

Impact of war on oral health: a systematic review.

Aim: To systematically review the evidence from published literature about the impact of war on oral health among children and adults.

Methodology: The electronic search was carried out in the following databases Pubmed, Cochrane, Scopus, Embase, Google Scholar. In vitro studies, cross-sectional, case control studies, and randomized controlled trials conducted during the war time were included.

Effectiveness of an oral health promotion training program among school nurses in India.

Background: Schools are a valuable platform for oral health promotion and the role of school nurse is critical in promoting oral health of children. A training program was carried out to assess its effectiveness in promoting oral health among school nurses of Navodaya Vidyalaya Samiti (NVS), one of the largest groups of central schools in India.

Methodology: A total of 557 school nurses of Navodaya Vidyalaya schools participated in the training program.

Influence of intracanal medicaments on the periodontal and periapical healing in concurrent endodontic-periodontal lesions with/without communication: a systematic review and meta-analysis.

Objectives: The purpose of this review is to determine the effectiveness of intracanal medicament (ICM) on periodontal and periapical healing (PH) of concurrent endodontic-periodontal lesions with/without communication in permanent teeth.

Materials And Methods: The pre-defined protocol was registered in PROSPERO, and a literature search using keywords was conducted on PubMed, Scopus, Cochrane, Embase electronic databases, and Gray literature and was hand-searched until August 2023. Two reviewers independently screened the title and abstracts using the inclusion criteria.

Oral hygiene status in individuals with hearing difficulties: A systematic review and meta-analysis.

Objectives: Most studies focusing on oral hygiene status in hearing impaired individuals are cross-sectional and focus on specific populations. A comprehensive literature search and evidence-based analysis was carried out to assess the oral hygiene status in this special group of population.

Methods: Searches were conducted in four databases with no restriction on publication date.

Effect of Intracanal Scaffolds on the Success Outcomes of Regenerative Endodontic Therapy - A Systematic Review and Network Meta-analysis.

Introduction: The scaffolds used in regenerative endodontic therapy (RET) provide structural support for cells so that they can adhere to the scaffolds and also are crucial for cellular proliferation and differentiation. The objective of this network meta-analysis was to compare effects of different intracanal scaffolds on success outcomes of RET.

Methods: PubMed/Medline, EMBASE, Cochrane, CINAHL, Scopus, and Web of Science databases were searched.

Effectiveness of a Training Program in School Teachers on the Role of Sugars in Oral and General Health.

Background: Schools have a powerful influence on children's development and well-being, and school teachers are considered role models to transmit life values and instill health-related behaviors. The effectiveness of a training program for school teachers in understanding the role of sugars and their impact on oral and overall health has not been previously reported.

Aim: The present study aimed to assess the effectiveness of a training program for school teachers on the role of sugars in oral and general health.

Dental caries status in individuals with hearing difficulties: A systematic review and meta-analysis.

Aims: The purpose of the systematic review and meta-analysis was to assess the dental caries status in individuals with hearing difficulties.

Methods And Results: Searches were conducted in six databases with no restriction on publication date. The cross-sectional and comparative cross sectional studies assessing the dental caries status of hearing impaired individuals using standardized evaluation criteria were included.

Effectiveness of Fluoride Varnish in Prevention of Early Childhood Caries in 3-4 Years Old Children - A 36 Month Prospective Community Based Randomized Controlled Trial.

Background: Evidence for the benefit of applying Fluoride Varnish FV to permanent teeth is generally very positive. However, the caries-inhibiting effect of FVs on primary teeth is still debatable.

Aim: To assess the effectiveness of fluoride varnish in prevention of early childhood caries in children over the period of 3 years in high fluoride areas.

Effectiveness of topical fluorides in prevention of radiation caries in adults: A systematic review and meta- analysis.

Background: Topical fluoride is used for prevention of dental caries. However, its effectiveness and more specifically its formulation and frequency of application in patients undergoing head and neck radiotherapy are still debatable. The aim of this systematic review was to pool the evidence of effectiveness of various topical fluorides in preventing radiation caries or change in bacterial growth in adult patients of head and neck cancer.

Determinants for tabacco cessation amongst smokers visiting tertiary health care centre in India.

Background: In India, 92.4% of adults believe that smoking causes serious illness. However, only 55.

Effectiveness of an oral health training program for nursing professionals in India: An interventional study.

Objectives: Nursing professionals form the first line of contact and are in a unique place to provide appropriate oral advice to patients. The study assessed the effectiveness of oral health training program for nurses.

Design: The effectiveness of the program was evaluated by a pre and post questionnaire assessment on 50 nurses.

The effect of energy and fat content labeling on food consumption pattern: a systematic review and meta-analysis.

Context: Consumption of high-energy food has increased globally, thereby leading to an increase in many diseases. One strategy for addressing this is to make people aware of their energy intake through energy and fat labels. However, the effectiveness of this remains debatable.

Oral health perception and plight of patients of schizophrenia.

Objective: To assess the oral health status, perception and dental treatment needs in patients of schizophrenia in the hospital set-up in Rohtak district, Haryana.

Methods And Result: A cross-sectional study was conducted to assess the oral health in patients of schizophrenia at Postgraduate Institute of Medical Sciences, Rohtak, Haryana amongst patients with ≤48 score on BPRS. A modified Dental Coping Belief Scale along with a structured questionnaire and clinical examination were recorded.

Effectiveness of oral health education on oral hygiene status among schizophrenic patients: A randomized controlled study.

Aim: The study aims to assess the effectiveness of oral health education on oral hygiene status among schizophrenic patients.

Methods And Results: A randomized parallel controlled trial was conducted among schizophrenic patients (n = 111) with BPR score of ≤ 48 to assess the role of oral health education on their oral hygiene status. The experimental group (n = 56) received oral health education while the control group (n = 55) were administered standard care advice.

Effect of post space preparation on the sealing ability of mineral trioxide aggregate and Gutta-percha: A bacterial leakage study.

Aim: The purpose of this study was to evaluate the effect of post space preparation on the sealing ability of teeth obturated with mineral trioxide aggregate (MTA) and Gutta-percha.

Materials And Methods: Fifty intact human mandibular premolars, after decoronation and biomechanical preparation, were randomly divided into three experimental groups. In Group A (n = 10), the canals were obturated with Gutta-percha using cold lateral compaction technique, followed by immediate post space preparation.

Modulation of decoding fidelity by ribosomal proteins S4 and S5.

Ribosomal proteins S4 and S5 participate in the decoding and assembly processes on the ribosome and the interaction with specific antibiotic inhibitors of translation. Many of the characterized mutations affecting these proteins decrease the accuracy of translation, leading to a ribosomal-ambiguity phenotype. Structural analyses of ribosomal complexes indicate that the tRNA selection pathway involves a transition between the closed and open conformations of the 30S ribosomal subunit and requires disruption of the interface between the S4 and S5 proteins.

Diverse effects of residues 74-78 in ribosomal protein S12 on decoding and antibiotic sensitivity.

Ribosomal protein S12 plays key roles in the ribosome's response to the error-promoting antibiotic streptomycin and in modulating the accuracy of translation. The discovery that substitutions at His76 in S12, distant from the streptomycin binding site, conferred streptomycin resistance in the thermophilic bacterium Thermus thermophilus prompted us to make similar alterations in the S12 protein of Escherichia coli. While, none of the E.

Community prevalence of methicillin and vancomycin resistant Staphylococcus aureus in and around Bangalore, southern India.

Introduction: Staphylococcus aureus is a known colonizer in humans and has been implicated in community acquired soft tissue infections. However emergence of methicillin resistant S. aureus(MRSA) has aroused great concern worldwide.

Error-prone and error-restrictive mutations affecting ribosomal protein S12.

Ribosomal protein S12 plays a pivotal role in decoding functions on the ribosome. X-ray crystallographic analyses of ribosomal complexes have revealed that S12 is involved in the inspection of codon-anticodon pairings in the ribosomal A site, as well as in the succeeding domain rearrangements of the 30S subunit that are essential for accommodation of aminoacyl-tRNA. A role for S12 in tRNA selection is also well supported by classical genetic analyses; mutations affecting S12 are readily isolated in bacteria and organelles, since specific alterations in S12 confer resistance to the error-inducing antibiotic streptomycin, and the ribosomes from many such streptomycin-resistant S12 mutants display decreased levels of miscoding.

Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virus.

The herpes simplex virus (HSV) virion host shutoff (Vhs) protein is an endoribonuclease that accelerates decay of many host and viral mRNAs. Purified Vhs does not distinguish mRNAs from nonmessenger RNAs and cuts target RNAs at many sites, yet within infected cells it is targeted to mRNAs and cleaves those mRNAs at preferred sites including, for some, regions of translation initiation. This targeting may result in part from Vhs binding to the translation initiation factor eIF4H; in particular, several mutations in Vhs that abrogate its binding to eIF4H also abolish its mRNA-degradative activity, even though the mutant proteins retain endonuclease activity.