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The Iron Age period occupies an important place in French history because the Gauls are regularly presented as the direct ancestors of the extant French population. We documented here the genomic diversity of Iron Age communities originating from six French regions. The 49 acquired genomes permitted us to highlight an absence of discontinuity between Bronze Age and Iron Age groups in France, lending support to a cultural transition linked to progressive local economic changes rather than to a massive influx of allochthone groups. Genomic analyses revealed strong genetic homogeneity among the regional groups associated with distinct archaeological cultures. This genomic homogenization appears to be linked to individuals' mobility between regions and gene flow with neighbouring groups from England and Spain. Thus, the results globally support a common genomic legacy for the Iron Age population of modern-day France that could be linked to recurrent gene flow between culturally differentiated communities.
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http://dx.doi.org/10.1016/j.isci.2022.104094 | DOI Listing |
J Clin Periodontol
September 2025
Department of Oral and Maxillofacial Surgery and Periodontology, Ribeirao Preto School of Dentistry, University of Sao Paulo (USP), Ribeirao Preto, Brazil.
Aim: To characterise periodontal and faecal microbiomes of individuals with periodontal health (PH) and diseases, and evaluate associations with periodontal, sociodemographic, anthropometric, nutritional and lifestyle factors.
Materials And Methods: Dental biofilm and faecal samples from individuals (n = 24/group) with PH, gingivitis (GG) and periodontitis (PE) were sequenced (16S rRNA). Anthropometric data and questionnaires on demographics, lifestyle, diet and intestinal habits were collected.
Environ Res
September 2025
Institute of Environmental Medicine, Karolinska Institutet, Solnavägen 4, SE-113 65 Stockholm, SWEDEN.
Cardiovascular disease (CVD) is the leading cause of death in Europe, with myocardial infarction (MI) being one of its most severe manifestations. While many risk factors for CVD are well known, occupational exposures remain relatively understudied-especially in analyses that adjust for co-occurring workplace exposures. This study aimed to examine the association between occupational exposure to chemicals and particles and the risk of first-time MI.
View Article and Find Full Text PDFClin Nutr ESPEN
September 2025
Department of Microbiology & Biotechnology, University School of Sciences, Gujarat University, Ahmedabad 380009, Gujarat, India; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia. Electronic addr
Background & Aims: Nutritional anemia is a widespread public health issue, impacting about one-quarter of the global population (24.3% in 2021; ∼1.92 billion people).
View Article and Find Full Text PDFNutrition
July 2025
Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA; Vitamin Angel Alliance, Goleta, California, USA.
Maternal undernutrition in Africa remains a public health challenge, contributing to negative pregnancy outcomes, neonatal mortality, and perpetuating intergenerational cycles of poor health. Antenatal multiple micronutrient supplementation (MMS), a cost-effective intervention recognized for its potential to improve maternal and neonatal health, reduces risks of low birth weight, preterm birth, small for gestational age, and stillbirth while offering a $37 return for every $1 invested. Despite its benefits, MMS adoption across African countries remains suboptimal.
View Article and Find Full Text PDFOncol Res Treat
September 2025
Background: Ovarian cancer is a prevalent and highly lethal gynaecological cancer. Among its various subtypes, epithelial ovarian cancer predominates, comprising of ten distinct subtypes and contributing significantly to the overall burden of ovarian malignancies. Concurrently, endometriosis, characterised by the ectopic growth of endometrial tissue within the pelvis, affects a substantial number of women of reproductive age.
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