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This study reports on the green and cost-efficient synthesis of gold nanoparticles from three different red algae extracts. The nanoparticles synthesized were fully characterized by UV-Vis spectroscopy, HRTEM, and Z-potential. Relevant components occurring in the extracts, such as polysaccharides or phenolic content, were assessed by analytical techniques such as spectrophotometric assays and liquid chromatography. Finally, the antioxidant, antitumoral, and anti-inflammatory potential of both the extracts and the gold nanoparticles synthesized were analyzed in order to determine a possible synergistic effect on the nanoparticles. The results obtained confirmed the obtainment of gold nanoparticles with significant potential as immunotherapeutic agents. The therapeutic potential of these nanoparticles could be higher than that of inert gold nanoparticles loaded with bioactive molecules since the former would allow for higher accumulation into the targeted tissue.
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http://dx.doi.org/10.3390/md20030182 | DOI Listing |
Analyst
September 2025
Functional Nanomaterial-based Chemical and Biological Sensing Technology Innovation Team of Department of Education of Yunnan Province, Yunnan Minzu University, Kunming 650504, P. R. China.
Copper ions are essential elements in the human body and participate in various physiological activities in the bodies of organisms. Herein, an ultrasensitive electrochemical biosensor was developed for detection of copper ions (Cu) based on FeO@Au magnetic nanoparticles (FeO@Au MNPs) and a Cu-dependent DNAzyme assisted nicking endonuclease signal amplification (NESA) strategy. dsDNA is formed by a hybridization reaction between DNA S2 and S1 immobilized on the surface of FeO@Au MNPs.
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September 2025
School of Information Science and Technology, Fudan University, 220 Handan Rd, Shanghai 200433, China.
Mercury(II) ions (Hg) are one of the most common and highly toxic heavy metal ions, which can contaminate the environment and damage the human health. Therefore, the precise detection of trace Hg concentration is particularly important. Herein, gold nanoparticles-enhanced silver-coated hollow fiber (HF) surface plasmon resonance (SPR) sensor was developed for the highly sensitive detection of Hg ions.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Measurement Technology & Instrumentation Key Laboratory of Hebei Province, Institute of Electrical Engineering, Yanshan University, Qinhuangdao, 066004, China.
Background: With the development of modern agriculture, neonicotinoid pesticides have been widely used due to their high efficiency and strong systemic properties. However, excessive use leads to the accumulation of residues in the food chain, threatening the ecosystem and human health. Pesticide residues are easily accumulated in oilseed crops and become concentrated during the edible oil refining process.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China. Electronic address:
Background: During intense exercise, anaerobic metabolism predominantly produces energy in the body, resulting in lactic acid (LA) accumulation, which contributes to muscle fatigue and soreness and may also impair neurological and cardiovascular functions. In endurance sports, the lactate threshold (LT) is a key indicator of an athlete's capacity to clear and utilize LA, directly influencing athletic performance and endurance. Therefore, LA detection is crucial for assessing the physical condition of both athletes and the general population, as well as for optimizing training programs.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
September 2025
Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA 19104, USA. Electronic address:
The clinical demand for safer, more precise, and functionally versatile imaging tools has intensified with the increasing complexity of disease diagnosis and management. Despite major strides in imaging technologies such as MRI, CT, USG, and PET/SPECT, many modalities are grappled by issues including low specificity, high systemic toxicity of contrast agents, and limited ability to provide real-time functional data. Dreaded by these shortcomings, nanotechnology-based approaches such as liposomes, quantum dots (QDs), polymeric nanoparticles (NPs), gold NPs, lipid NPs, and metallic NPs have emerged as promising alternatives.
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