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[This retracts the article DOI: 10.3892/etm.2018.6223.].
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http://dx.doi.org/10.3892/etm.2022.11227 | DOI Listing |
Exp Ther Med
April 2022
[This retracts the article DOI: 10.3892/etm.2018.
View Article and Find Full Text PDFMol Med Rep
January 2021
Department of Thyroid Surgery, The First Hospital of Qiqihar, Affiliated Qiqihar Hospital, Southern Medical University, Qiqihar, Heilongjiang 161000, P.R. China.
At present, treatment options for thyroid carcinoma remain limited. The present study aimed to investigate the role of ZFAS1 in various major hallmarks of cancer and the underlying mechanisms in thyroid carcinoma cells. The interactions between long non‑coding RNAs (lncRNAs), microRNAs (miRs) and target genes were predicted by bioinformatics and confirmed by performing dual‑luciferase assays.
View Article and Find Full Text PDFFront Immunol
May 2021
Department of Biomedical Sciences, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, United States.
Mitophagy has recently been implicated in bacterial infection but the underlying mechanism remains largely unknown. Here, we uncover a role of microRNA-302/367 cluster in regulating mitophagy and its associated host response against bacterial infection. We demonstrate that miR-302/367 cluster expression was significantly increased after infection.
View Article and Find Full Text PDFExp Cell Res
November 2020
Department of Gynecology, Harbin Medical University Cancer Hospital, Harbin, China. Electronic address:
Epithelial-mesenchymal transition (EMT) is an important contributor to drug resistance in ovarian cancer. The aims of this study were to explore the potential role of the miR-302 cluster in modulating EMT and cisplatin resistance in ovarian cancer. We used qRT-PCR and western blotting to show that miR-302 expression was lower in chemoresistant than in chemosensitive cells, and miR-302 was upregulated in chemosensitive, but not chemoresistant ovarian cancer cells in response to cisplatin treatment.
View Article and Find Full Text PDFEur Rev Med Pharmacol Sci
September 2019
Department of Internal Medicine, Yanbian University, Yanji, Jilin, China.
Objective: Hepatocellular carcinoma (HCC) is a hypervascularized tumor. Aberrant angiogenesis is the main cause, which results in cancer growth and progression. It has been showed that microRNA-302 cluster (miR-302) may be associated with angiogenesis.
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