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http://dx.doi.org/10.1097/CM9.0000000000001907 | DOI Listing |
Plant J
September 2025
College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Genome imbalance, resulting from varying the dosage of individual chromosomes (aneuploidy), has a more detrimental effect than changes in complete sets of chromosomes (haploidy/polyploidy). This imbalance is likely due to disruptions in stoichiometry and interactions among macromolecular assemblies. Previous research has shown that aneuploidy causes global modulation of protein-coding genes (PCGs), microRNAs, and transposable elements (TEs), affecting both the varied chromosome (cis-located) and unvaried genome regions (trans-located) across various taxa.
View Article and Find Full Text PDFClin Transplant
September 2025
Avera Medical Group Transplant & Liver Surgery, Avera McKennan Hospital & University Health Center, Sioux Falls, South Dakota, USA.
Background: In the United States, a severe organ shortage precipitates an extensive transplant waitlist. Living donor kidneys are functionally superior to those from deceased donors and offer an alternative to close the supply-demand gap.
Methods: A retrospective review of 2147 patients who self-referred to begin the living kidney donation workup process at our center between June 1, 2012, and October 1, 2023 was conducted with subsequent statistical analysis of gathered data.
PLoS One
September 2025
School of Statistics and Mathematics, Zhongnan University of Economics and Law, Wuhan, China.
This research delves into the optimization of urbanization spatial patterns in Guizhou Province, China. The findings reveal that with regional coordinated development as the central objective and the optimization of urbanization spatial patterns as the strategic focus, a research framework encompassing "temporal and spatial evolution of urbanization - identification and summation of pain points and difficulties - scenario simulation and optimization - strategic goal selection" is utilized to specifically tackle issues pertaining to urbanization spatial patterns. Through the construction of diverse scenarios and rigorous research analysis, an implementation pathway is derived, advocating for "strengthening the central region of Guizhou, fostering urban agglomeration development, reinforcing developmental support points, and promoting regional coordinated development.
View Article and Find Full Text PDFPLoS One
September 2025
University of Health and Allied Sciences, Volta Region-Ho, Ghana.
Introduction: The alarming rate of drug-resistant tuberculosis (DR-TB) globally is a threat to treatment success among positive tuberculosis (TB) cases. Studies aimed at determining the prevalence, trend of DR-TB and socio-demographic and clinical risk factors contributing to DR-TB in the four regions of Ghana are currently unknown. This study sought to determine the prevalence and trend of DR-TB, identify socio-demographic and clinical risk factors that influence DR-TB, and analyse the relationship between underweight and adverse drug reactions and treatment outcomes among DR-TB patients in four regions of Ghana.
View Article and Find Full Text PDFPLoS One
September 2025
School of Emergency Technology, Guangzhou Vocational College of Technology and Business, Guangzhou, China.
Under China's national sustainability strategy, the logistics industry is confronted with the imperative of high-quality green development. Given its status as the leading economic province and a national logistics hub, investigating green logistics development in Guangdong province holds paramount strategic importance. To comprehensively evaluate green logistics development efficiency of 21 cities in Guangdong from 2016 to 2022, this study employed the super-efficiency slacks-based measure model (Super-SBM) with undesirable outputs, the Global Malmquist-Luenberger (GML) productivity index and a four-quadrant analysis based on static and dynamic efficiency.
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