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Purpose: Conventional catheter ablation for atrial fibrillation requires fluoroscopy, which has inherent risks of radiation exposure to patients and medical staff. Optimization of fluoroscopy parameters and use of three-dimensional electroanatomic mapping (EAM) and intracardiac echocardiography (ICE) have helped to reduce radiation exposure; however, despite growing evidence, there are still concerns about safety and added procedure time associated with fluoroless procedures, particularly in left-sided ablations, due to the potential risk of complications. Herein, we report our initial experience using a radiofrequency (RF) wire for completely fluoroless radiofrequency ablation (RFA) and cryoballoon ablation (CBA).
Methods: A retrospective analysis was conducted on ablation procedures for various cardiac arrhythmias performed non-fluoroscopically at two centers using the VersaCross RF wire transseptal system under EAM and ICE guidance.
Results: A total of 72 and 54 patients underwent RFA and CBA, respectively, successfully without any procedural complications. Transseptal access time for RFA was 14.5 ± 6.6 min from procedure start (including sheath and catheter placements ± right-sided ablation) or 2.8 ± 1.0 min from RF wire insertion into the femoral introducer. Transseptal access time for CBA was 19.2 ± 11.7 min from procedure start (including sheath and catheter placements ± right-sided ablation) or 3.5 ± 1.6 min from RF wire insertion into the femoral introducer. Average procedure time was 104.4 ± 38.0 min for RFA and 91.1 ± 22.1 min for CBA.
Conclusions: A RF wire can be used to achieve completely fluoroless transseptal puncture safely and effectively while improving procedural efficiency in both RFA and CBA.
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http://dx.doi.org/10.1007/s10840-022-01157-5 | DOI Listing |
Front Bioeng Biotechnol
August 2025
Navy Special Medical Centre, Second Military Medical University, Shanghai, China.
Radiation exposure initiates a cascade of reactions, including the release of reactive oxygen species, DNA double-strand breaks, and cellular apoptosis, leading to cell death, tissue damage, and potentially the development of cancer. Consequently, there is an urgent need to develop highly effective and low-toxicity radioprotective agents. Traditional chemically synthesized protective agents face significant limitations in clinical applicability due to their pronounced off-target toxicity, narrow therapeutic window, and high production costs.
View Article and Find Full Text PDFFront Fungal Biol
August 2025
Department of Crop Science, University of Ghana, Accra, Ghana.
Chili pepper exports from Ghana are subject to stringent chemical residue regulations in key export destinations. Consequently, microbial biopesticides are urgently needed to complement current nonchemical control options for key pests of chili pepper, particularly the phytosanitary insect, False Codling Moth (FCM). Thus, the search for native entomopathogenic fungi in Ghanaian farms was initiated in 2023.
View Article and Find Full Text PDFAntimicrob Steward Healthc Epidemiol
September 2025
Center for Access and Delivery Research and Evaluation (CADRE), Iowa City VA Healthcare System, Iowa City, IA, USA.
Background: Ultraviolet-C (UV-C) radiation has emerged as a widely adopted disinfection technology in healthcare settings due to its germicidal effectiveness. However, concerns have grown regarding the potential degradation of materials, particularly polymeric surfaces, subjected to repeated UV-C exposure. Understanding the extent, mechanism, and contributing factors of UV-C-induced material degradation is essential for safe and sustainable implementation.
View Article and Find Full Text PDFRev Bras Ortop (Sao Paulo)
June 2025
Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brazil.
Objective: The present study aimed to compare the accuracy of the Paprosky Classification of Femoral Bone Loss using plain radiographs and two-dimensional computed tomography (2D CT) images with the femoral defect observed intraoperatively by the surgeon.
Methods: There were 14 hip surgeons from the same hospital who classified 80 patients with an indication for revision hip arthroplasty according to Paprosky based on plain radiographs in anteroposterior views of the pelvis and 2D CT images, reconstructed in the axial, coronal, and sagittal planes. We compared this data with the intraoperative findings of femoral bone loss by the same surgeons.
Rev Bras Ortop (Sao Paulo)
June 2025
Instituto Nacional de Traumatologia e Ortopedia Jamil Haddad, Rio de Janeiro, RJ, Brasil.
Objective: The present study aimed to compare the accuracy of the Paprosky Classification of Femoral Bone Loss using plain radiographs and two-dimensional computed tomography (2D CT) images with the femoral defect observed intraoperatively by the surgeon.
Methods: There were 14 hip surgeons from the same hospital who classified 80 patients with an indication for revision hip arthroplasty according to Paprosky based on plain radiographs in anteroposterior views of the pelvis and 2D CT images, reconstructed in the axial, coronal, and sagittal planes. We compared this data with the intraoperative findings of femoral bone loss by the same surgeons.