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Differences in health outcomes across racial groups are among the most commonly reported findings in health disparities research. Often, these studies do not explicitly connect observed disparities to mechanisms of systemic racism that drive adverse health outcomes among racialized and other marginalized groups in the United States. Without this connection, investigators inadvertently support harmful narratives of biologic essentialism or cultural inferiority that pathologize racial identities and inhibit health equity. This paper outlines pitfalls in the conceptualization, contextualization, and operationalization of race in quantitative population health research and provides recommendations on how to appropriately engage in scientific inquiry aimed at understanding racial health inequities. Race should not be used as a measure of biologic difference, but rather as a proxy for exposure to systemic racism. Future studies should go beyond this proxy use and directly measure racism and its health impacts.Appeared as "Online First" article.
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http://dx.doi.org/10.1370/afm.2792 | DOI Listing |
J Racial Ethn Health Disparities
September 2025
Georgetown University Medical Center, Washington, DC, USA.
Introduction: Hispanics are over-represented in outdoor occupations; therefore they face an elevated risk of skin cancer. However, there is limited research examining these workers' self-risk perceptions and sun-protective behaviors. This study explores Hispanic outdoor workers' knowledge, attitudes, barriers, and facilitators for engaging in sun-protective behaviors to inform a culturally-tailored intervention.
View Article and Find Full Text PDFClin Pharmacol Drug Dev
September 2025
Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Safety, pharmacokinetics, and impact of race of pharmacokinetics on monoclonal antibodies tixagevimab and cilgavimab (AZD7442) were assessed in Chinese adult participants in a Phase 2, randomized, double-blind, placebo-controlled trial. In total, 272 participants were randomized 3:1 to a single intravenous dose of 600 mg AZD7442 or placebo and followed for 451 days. Mean participant age was 34.
View Article and Find Full Text PDFHepatol Commun
September 2025
Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Background: In Michigan, Asian Americans are disproportionately infected with HBV and HCV. As many infections are first diagnosed when patients present with advanced liver disease or liver cancer, HBV and HCV screening, awareness, and early treatment are critical to improving outcomes.
Methods: Using a theory-informed approach, we administered a bi-level qualitative study to identify determinants of viral hepatitis and liver cancer care and treatment in Michigan Asian American communities.
AIDS Educ Prev
August 2025
School of Nursing, Rutgers University, Newark, New Jersey.
Introduction: Black, Latine, and Caribbean (BLC) sexual and gender minorities (SGM) face structural HIV inequities. Sociocentric interventions may address these barriers, but it is unclear if respondent-driven sampling (RDS) can recruit existing BLC SGM friendship groups or if sociocentric HIV prevention interventions are feasible.
Methods: Using an exploratory mixed-methods design (August/2022-January/2024, New York, NY), we recruited participants into a sociocentric RDS group (sRDS) or an individual-level peer referral (PR) group, with qualitative interviews drawn from quantitative participants.
J Gen Intern Med
September 2025
Health, Homelessness, and Criminal Justice Lab, Hennepin Healthcare Research Institute, Minneapolis, MN, USA.
Background: Public health data systems have limited ability to provide timely, population-level information for people with severe and multiple disadvantages, such as individuals with recent homelessness or incarceration.
Objective: To generate prevalence estimates for physical health, mental health, and substance use conditions in a statewide cohort that included individuals with recent incarceration or homelessness.
Design: This observational cohort analysis was completed in July 2025 and used linked statewide electronic health record (EHR) and administrative data through the Minnesota Electronic Health Record Consortium (MNEHRC) and its Health Trends Across Communities project.